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1tx3

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{{Seed}}
 
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[[Image:1tx3.png|left|200px]]
 
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==HINCII BOUND TO COGNATE DNA==
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The line below this paragraph, containing "STRUCTURE_1tx3", creates the "Structure Box" on the page.
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<StructureSection load='1tx3' size='340' side='right'caption='[[1tx3]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1tx3]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TX3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TX3 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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{{STRUCTURE_1tx3| PDB=1tx3 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tx3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tx3 OCA], [https://pdbe.org/1tx3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tx3 RCSB], [https://www.ebi.ac.uk/pdbsum/1tx3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tx3 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/T2C2_HAEIF T2C2_HAEIF] Recognizes the double-stranded sequence GTYRAC and cleaves after Y-3.
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===HINCII BOUND TO COGNATE DNA===
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==See Also==
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*[[Endonuclease 3D structures|Endonuclease 3D structures]]
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__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 15491133 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15491133}}
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==About this Structure==
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1TX3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TX3 OCA].
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==Reference==
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Ca2+ binding in the active site of HincII: implications for the catalytic mechanism., Etzkorn C, Horton NC, Biochemistry. 2004 Oct 26;43(42):13256-70. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15491133 15491133]
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Sequence selectivity and degeneracy of a restriction endonuclease mediated by DNA intercalation., Horton NC, Dorner LF, Perona JJ, Nat Struct Biol. 2002 Jan;9(1):42-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11742344 11742344]
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[[Category: Haemophilus influenzae]]
[[Category: Haemophilus influenzae]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Type II site-specific deoxyribonuclease]]
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[[Category: Dorner LF]]
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[[Category: Dorner, L F.]]
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[[Category: Horton NC]]
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[[Category: Horton, N C.]]
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[[Category: Perona JJ]]
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[[Category: Perona, J J.]]
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[[Category: Blunt cutting]]
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[[Category: Dna bending]]
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[[Category: Indirect readout]]
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[[Category: Protein-dna]]
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[[Category: Restriction endonuclease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 13:22:05 2008''
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Current revision

HINCII BOUND TO COGNATE DNA

PDB ID 1tx3

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