3cf4

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{{Seed}}
 
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[[Image:3cf4.png|left|200px]]
 
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==Structure of the CODH component of the M. barkeri ACDS complex==
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The line below this paragraph, containing "STRUCTURE_3cf4", creates the "Structure Box" on the page.
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<StructureSection load='3cf4' size='340' side='right'caption='[[3cf4]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3cf4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanosarcina_barkeri Methanosarcina barkeri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CF4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CF4 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=CMO:CARBON+MONOXIDE'>CMO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=WCC:FE(3)-NI(1)-S(4)+CLUSTER'>WCC</scene></td></tr>
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{{STRUCTURE_3cf4| PDB=3cf4 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cf4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cf4 OCA], [https://pdbe.org/3cf4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cf4 RCSB], [https://www.ebi.ac.uk/pdbsum/3cf4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cf4 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ACDA1_METBF ACDA1_METBF] Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.[HAMAP-Rule:MF_01137]<ref>PMID:6425262</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cf/3cf4_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cf4 ConSurf].
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<div style="clear:both"></div>
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===Structure of the CODH component of the M. barkeri ACDS complex===
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==See Also==
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*[[Acetyl-CoA synthase 3D structures|Acetyl-CoA synthase 3D structures]]
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 18621675 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_18621675}}
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==About this Structure==
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3CF4 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Methanosarcina_barkeri Methanosarcina barkeri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CF4 OCA].
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==Reference==
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Structure of the alpha2epsilon2 Ni-dependent CO dehydrogenase component of the Methanosarcina barkeri acetyl-CoA decarbonylase/synthase complex., Gong W, Hao B, Wei Z, Ferguson DJ Jr, Tallant T, Krzycki JA, Chan MK, Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9558-63. Epub 2008 Jul 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18621675 18621675]
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[[Category: Methanosarcina barkeri]]
[[Category: Methanosarcina barkeri]]
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[[Category: Protein complex]]
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[[Category: Chan MK]]
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[[Category: Chan, M K.]]
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[[Category: Ferguson Jr DJ]]
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[[Category: Gong, W.]]
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[[Category: Gong W]]
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[[Category: Hao, B.]]
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[[Category: Hao B]]
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[[Category: Jr., D J.Ferguson.]]
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[[Category: Krzycki JA]]
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[[Category: Krzycki, J A.]]
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[[Category: Tallant T]]
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[[Category: Tallant, T.]]
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[[Category: Wei Z]]
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[[Category: Wei, Z.]]
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[[Category: 4fe-ni-4]]
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[[Category: Iron-nikel-sulfur]]
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[[Category: Methanomicrobia]]
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[[Category: Oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 13:40:28 2008''
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Current revision

Structure of the CODH component of the M. barkeri ACDS complex

PDB ID 3cf4

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