2pun

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{{Seed}}
 
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[[Image:2pun.png|left|200px]]
 
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<!--
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==Structures of 5-methylthioribose kinase reveal substrate specificity and unusual mode of nucleotide binding==
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The line below this paragraph, containing "STRUCTURE_2pun", creates the "Structure Box" on the page.
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<StructureSection load='2pun' size='340' side='right'caption='[[2pun]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2pun]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PUN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PUN FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CPS:3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE'>CPS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SR1:5-S-METHYL-5-THIO-ALPHA-D-RIBOFURANOSE'>SR1</scene></td></tr>
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{{STRUCTURE_2pun| PDB=2pun | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pun OCA], [https://pdbe.org/2pun PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pun RCSB], [https://www.ebi.ac.uk/pdbsum/2pun PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pun ProSAT]</span></td></tr>
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</table>
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===Structures of 5-methylthioribose kinase reveal substrate specificity and unusual mode of nucleotide binding===
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== Function ==
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[https://www.uniprot.org/uniprot/MTNK_BACSU MTNK_BACSU] Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.<ref>PMID:11545674</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_17522047}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 17522047 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pu/2pun_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_17522047}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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2PUN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PUN OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pun ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Structures of 5-methylthioribose kinase reveal substrate specificity and unusual mode of nucleotide binding., Ku SY, Yip P, Cornell KA, Riscoe MK, Behr JB, Guillerm G, Howell PL, J Biol Chem. 2007 Jul 27;282(30):22195-206. Epub 2007 May 23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17522047 17522047]
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<references/>
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__TOC__
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</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: S-methyl-5-thioribose kinase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Ku S-Y]]
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[[Category: Ku, S Y.]]
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[[Category: 5-methylthioribose kinase]]
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[[Category: Methionine recycling pathway]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 13:41:47 2008''
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Current revision

Structures of 5-methylthioribose kinase reveal substrate specificity and unusual mode of nucleotide binding

PDB ID 2pun

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