1om1

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{{Seed}}
 
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[[Image:1om1.png|left|200px]]
 
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==Crystal structure of maize CK2 alpha in complex with IQA==
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The line below this paragraph, containing "STRUCTURE_1om1", creates the "Structure Box" on the page.
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<StructureSection load='1om1' size='340' side='right'caption='[[1om1]], [[Resolution|resolution]] 1.68&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1om1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OM1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OM1 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.68&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IQA:(5-OXO-5,6-DIHYDRO-INDOLO[1,2-A]QUINAZOLIN-7-YL)-ACETIC+ACID'>IQA</scene></td></tr>
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{{STRUCTURE_1om1| PDB=1om1 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1om1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1om1 OCA], [https://pdbe.org/1om1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1om1 RCSB], [https://www.ebi.ac.uk/pdbsum/1om1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1om1 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CSK2A_MAIZE CSK2A_MAIZE] Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha chain contains the catalytic site.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/om/1om1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1om1 ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of maize CK2 alpha in complex with IQA===
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==See Also==
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*[[Casein kinase 3D structures|Casein kinase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12816539}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12816539 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12816539}}
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==About this Structure==
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1OM1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OM1 OCA].
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==Reference==
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Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA)., Sarno S, de Moliner E, Ruzzene M, Pagano MA, Battistutta R, Bain J, Fabbro D, Schoepfer J, Elliott M, Furet P, Meggio F, Zanotti G, Pinna LA, Biochem J. 2003 Sep 15;374(Pt 3):639-46. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12816539 12816539]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Single protein]]
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[[Category: Zea mays]]
[[Category: Zea mays]]
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[[Category: Battistutta, R.]]
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[[Category: Battistutta R]]
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[[Category: Moliner, E De.]]
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[[Category: De Moliner E]]
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[[Category: Zanotti, G.]]
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[[Category: Zanotti G]]
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[[Category: Ck2]]
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[[Category: Inhibitor]]
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[[Category: Iqa]]
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[[Category: Zea may]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 14:31:14 2008''
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Current revision

Crystal structure of maize CK2 alpha in complex with IQA

PDB ID 1om1

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