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1nm8

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{{Seed}}
 
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[[Image:1nm8.png|left|200px]]
 
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==Structure of Human Carnitine Acetyltransferase: Molecular Basis for Fatty Acyl Transfer==
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The line below this paragraph, containing "STRUCTURE_1nm8", creates the "Structure Box" on the page.
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<StructureSection load='1nm8' size='340' side='right'caption='[[1nm8]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1nm8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NM8 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nm8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nm8 OCA], [https://pdbe.org/1nm8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nm8 RCSB], [https://www.ebi.ac.uk/pdbsum/1nm8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nm8 ProSAT]</span></td></tr>
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{{STRUCTURE_1nm8| PDB=1nm8 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CACP_HUMAN CACP_HUMAN] Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nm/1nm8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nm8 ConSurf].
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<div style="clear:both"></div>
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===Structure of Human Carnitine Acetyltransferase: Molecular Basis for Fatty Acyl Transfer===
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==See Also==
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*[[Carnitine acetyltransferase|Carnitine acetyltransferase]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12562770}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 12562770 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12562770}}
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==About this Structure==
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1NM8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NM8 OCA].
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==Reference==
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Structure of human carnitine acetyltransferase. Molecular basis for fatty acyl transfer., Wu D, Govindasamy L, Lian W, Gu Y, Kukar T, Agbandje-McKenna M, McKenna R, J Biol Chem. 2003 Apr 11;278(15):13159-65. Epub 2003 Jan 31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12562770 12562770]
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[[Category: Carnitine O-acetyltransferase]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Agbandje-McKenna, M.]]
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[[Category: Agbandje-McKenna M]]
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[[Category: Govindasamy, L.]]
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[[Category: Govindasamy L]]
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[[Category: Gu, Y.]]
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[[Category: Gu Y]]
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[[Category: Kukar, T.]]
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[[Category: Kukar T]]
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[[Category: Lian, W.]]
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[[Category: Lian W]]
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[[Category: McKenna, R.]]
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[[Category: McKenna R]]
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[[Category: Wu, D.]]
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[[Category: Wu D]]
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[[Category: Anti-parallel beta-strand]]
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[[Category: Two equally sized domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 15:13:25 2008''
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Current revision

Structure of Human Carnitine Acetyltransferase: Molecular Basis for Fatty Acyl Transfer

PDB ID 1nm8

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