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1sfc

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{{Seed}}
 
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[[Image:1sfc.png|left|200px]]
 
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==NEURONAL SYNAPTIC FUSION COMPLEX==
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The line below this paragraph, containing "STRUCTURE_1sfc", creates the "Structure Box" on the page.
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<StructureSection load='1sfc' size='340' side='right'caption='[[1sfc]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1sfc]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. The November 2013 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''SNARE Proteins'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2013_11 10.2210/rcsb_pdb/mom_2013_11]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SFC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SFC FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=SR:STRONTIUM+ION'>SR</scene></td></tr>
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{{STRUCTURE_1sfc| PDB=1sfc | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sfc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sfc OCA], [https://pdbe.org/1sfc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sfc RCSB], [https://www.ebi.ac.uk/pdbsum/1sfc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sfc ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/VAMP2_RAT VAMP2_RAT] Involved in the targeting and/or fusion of transport vesicles to their target membrane (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sf/1sfc_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sfc ConSurf].
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<div style="clear:both"></div>
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===NEURONAL SYNAPTIC FUSION COMPLEX===
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==See Also==
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*[[Syntaxin 3D structures|Syntaxin 3D structures]]
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*[[Vesicle-associated membrane protein|Vesicle-associated membrane protein]]
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__TOC__
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The line below this paragraph, {{ABSTRACT_PUBMED_9759724}}, adds the Publication Abstract to the page
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 9759724 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: RCSB PDB Molecule of the Month]]
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{{ABSTRACT_PUBMED_9759724}}
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==About this Structure==
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1SFC is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SFC OCA].
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==Reference==
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Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution., Sutton RB, Fasshauer D, Jahn R, Brunger AT, Nature. 1998 Sep 24;395(6700):347-53. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9759724 9759724]
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[[Category: Protein complex]]
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[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Brunger, A T.]]
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[[Category: SNARE Proteins]]
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[[Category: Sutton, R B.]]
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[[Category: Brunger AT]]
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[[Category: Membrane fusion protein complex]]
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[[Category: Sutton RB]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 15:36:35 2008''
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Current revision

NEURONAL SYNAPTIC FUSION COMPLEX

PDB ID 1sfc

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