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1tzf

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{{Seed}}
 
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[[Image:1tzf.png|left|200px]]
 
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==X-ray Crystal Structure of alpha-D-glucose-1-phosphate cytidylyltransferase from Salmonella typhi==
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The line below this paragraph, containing "STRUCTURE_1tzf", creates the "Structure Box" on the page.
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<StructureSection load='1tzf' size='340' side='right'caption='[[1tzf]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1tzf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhi_str._CT18 Salmonella enterica subsp. enterica serovar Typhi str. CT18]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TZF FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C5G:[CYTIDINE-5-PHOSPHATE]-BETA-GLUCOSYL-PHOSPHORIC+ACID+ESTER'>C5G</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_1tzf| PDB=1tzf | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tzf OCA], [https://pdbe.org/1tzf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tzf RCSB], [https://www.ebi.ac.uk/pdbsum/1tzf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tzf ProSAT]</span></td></tr>
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</table>
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===X-ray Crystal Structure of alpha-D-glucose-1-phosphate cytidylyltransferase from Salmonella typhi===
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== Function ==
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[https://www.uniprot.org/uniprot/RFBF_SALTI RFBF_SALTI] Involved in the biosynthesis of the tyvelose, a 3,6-dideoxyhexose found in the O-antigen of the surface lipopolysaccharides. It catalyzes the transfer of a CMP moiety from CTP to glucose 1-phosphate. This enzyme can utilize either CTP or UTP as the nucleotide donor.<ref>PMID:15634670</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_15292268}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 15292268 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tz/1tzf_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_15292268}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1TZF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhi Salmonella typhi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TZF OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tzf ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Molecular structure of alpha-D-glucose-1-phosphate cytidylyltransferase from Salmonella typhi., Koropatkin NM, Holden HM, J Biol Chem. 2004 Oct 15;279(42):44023-9. Epub 2004 Aug 3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15292268 15292268]
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<references/>
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[[Category: Glucose-1-phosphate cytidylyltransferase]]
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__TOC__
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[[Category: Salmonella typhi]]
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</StructureSection>
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Holden, H M.]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhi str. CT18]]
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[[Category: Koropatkin, N M.]]
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[[Category: Holden HM]]
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[[Category: Mixed alpha/beta fold]]
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[[Category: Koropatkin NM]]
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[[Category: Nucleotidyltransferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 15:36:54 2008''
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Current revision

X-ray Crystal Structure of alpha-D-glucose-1-phosphate cytidylyltransferase from Salmonella typhi

PDB ID 1tzf

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