1uaa

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{{Seed}}
 
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[[Image:1uaa.png|left|200px]]
 
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==E. COLI REP HELICASE/DNA COMPLEX==
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The line below this paragraph, containing "STRUCTURE_1uaa", creates the "Structure Box" on the page.
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<StructureSection load='1uaa' size='340' side='right'caption='[[1uaa]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1uaa]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UAA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UAA FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uaa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uaa OCA], [https://pdbe.org/1uaa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uaa RCSB], [https://www.ebi.ac.uk/pdbsum/1uaa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uaa ProSAT]</span></td></tr>
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{{STRUCTURE_1uaa| PDB=1uaa | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/REP_ECOLI REP_ECOLI] Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ua/1uaa_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1uaa ConSurf].
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<div style="clear:both"></div>
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===E. COLI REP HELICASE/DNA COMPLEX===
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==See Also==
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*[[Helicase|Helicase]]
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*[[Helicase 3D structures|Helicase 3D structures]]
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__TOC__
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The line below this paragraph, {{ABSTRACT_PUBMED_9288744}}, adds the Publication Abstract to the page
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 9288744 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9288744}}
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==About this Structure==
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1UAA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UAA OCA].
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==Reference==
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Major domain swiveling revealed by the crystal structures of complexes of E. coli Rep helicase bound to single-stranded DNA and ADP., Korolev S, Hsieh J, Gauss GH, Lohman TM, Waksman G, Cell. 1997 Aug 22;90(4):635-47. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9288744 9288744]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Escherichia coli K-12]]
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[[Category: Korolev, S.]]
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[[Category: Large Structures]]
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[[Category: Waksman, G.]]
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[[Category: Korolev S]]
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[[Category: Dna unwinding]]
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[[Category: Waksman G]]
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[[Category: Helicase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 15:57:51 2008''
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Current revision

E. COLI REP HELICASE/DNA COMPLEX

PDB ID 1uaa

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