2iop

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{{Seed}}
 
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[[Image:2iop.png|left|200px]]
 
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==Crystal Structure of Full-length HtpG, the Escherichia coli Hsp90, Bound to ADP==
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The line below this paragraph, containing "STRUCTURE_2iop", creates the "Structure Box" on the page.
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<StructureSection load='2iop' size='340' side='right'caption='[[2iop]], [[Resolution|resolution]] 3.55&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2iop]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IOP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IOP FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.55&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
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{{STRUCTURE_2iop| PDB=2iop | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iop FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iop OCA], [https://pdbe.org/2iop PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iop RCSB], [https://www.ebi.ac.uk/pdbsum/2iop PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iop ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HTPG_ECOLI HTPG_ECOLI] Molecular chaperone. Has ATPase activity.[HAMAP-Rule:MF_00505]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/io/2iop_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2iop ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of Full-length HtpG, the Escherichia coli Hsp90, Bound to ADP===
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==See Also==
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*[[Heat Shock Protein structures|Heat Shock Protein structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_17055434}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 17055434 is the PubMed ID number.
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{{ABSTRACT_PUBMED_17055434}}
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==About this Structure==
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2IOP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IOP OCA].
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==Reference==
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Structural Analysis of E. coli hsp90 reveals dramatic nucleotide-dependent conformational rearrangements., Shiau AK, Harris SF, Southworth DR, Agard DA, Cell. 2006 Oct 20;127(2):329-40. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17055434 17055434]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Agard, D A.]]
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[[Category: Agard DA]]
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[[Category: Harris, S F.]]
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[[Category: Harris SF]]
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[[Category: Shiau, A K.]]
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[[Category: Shiau AK]]
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[[Category: Chaperone]]
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[[Category: Heat shock protein]]
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[[Category: Hsp90]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 16:10:37 2008''
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Current revision

Crystal Structure of Full-length HtpG, the Escherichia coli Hsp90, Bound to ADP

PDB ID 2iop

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OCA

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