This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1qnf

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /><applet load="1qnf" size="450" color="white" frame="true" align="right" spinBox="true" caption="1qnf, resolution 1.8&Aring;" /> '''STRUCTURE OF PHOTOLYA...)
Current revision (08:15, 14 February 2024) (edit) (undo)
 
(15 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1qnf.gif|left|200px]]<br /><applet load="1qnf" size="450" color="white" frame="true" align="right" spinBox="true"
 
-
caption="1qnf, resolution 1.8&Aring;" />
 
-
'''STRUCTURE OF PHOTOLYASE'''<br />
 
-
==Overview==
+
==STRUCTURE OF PHOTOLYASE==
-
The crystal structure at 1.8 A resolution of 8-HDF type photolyase from A., nidulans shows a backbone structure similar to that of MTHF type E. coli, photolyase but reveals a completely different binding site for the, light-harvesting cofactor.
+
<StructureSection load='1qnf' size='340' side='right'caption='[[1qnf]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-
 
+
== Structural highlights ==
-
==About this Structure==
+
<table><tr><td colspan='2'>[[1qnf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Synechococcus_elongatus_PCC_6301 Synechococcus elongatus PCC 6301]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QNF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QNF FirstGlance]. <br>
-
1QNF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Synechococcus_sp. Synechococcus sp.] with FAD and HDF as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Deoxyribodipyrimidine_photo-lyase Deoxyribodipyrimidine photo-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.99.3 4.1.99.3] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1QNF OCA].
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=HDF:8-HYDROXY-10-(D-RIBO-2,3,4,5-TETRAHYDROXYPENTYL)-5-DEAZAISOALLOXAZINE'>HDF</scene></td></tr>
-
==Reference==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qnf OCA], [https://pdbe.org/1qnf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qnf RCSB], [https://www.ebi.ac.uk/pdbsum/1qnf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qnf ProSAT]</span></td></tr>
-
Crystal structure of DNA photolyase from Anacystis nidulans., Tamada T, Kitadokoro K, Higuchi Y, Inaka K, Yasui A, de Ruiter PE, Eker AP, Miki K, Nat Struct Biol. 1997 Nov;4(11):887-91. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9360600 9360600]
+
</table>
-
[[Category: Deoxyribodipyrimidine photo-lyase]]
+
== Function ==
-
[[Category: Single protein]]
+
[https://www.uniprot.org/uniprot/PHR_SYNP6 PHR_SYNP6] Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation.
-
[[Category: Synechococcus sp.]]
+
== Evolutionary Conservation ==
-
[[Category: Kitadokoro, K.]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: Miki, K.]]
+
Check<jmol>
-
[[Category: FAD]]
+
<jmolCheckbox>
-
[[Category: HDF]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qn/1qnf_consurf.spt"</scriptWhenChecked>
-
[[Category: dna repair]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: electron transfer]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: excitation energy transfer]]
+
</jmolCheckbox>
-
[[Category: lyase (carbon-carbon)]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qnf ConSurf].
-
 
+
<div style="clear:both"></div>
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 00:49:57 2007''
+
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Synechococcus elongatus PCC 6301]]
 +
[[Category: Kitadokoro K]]
 +
[[Category: Miki K]]

Current revision

STRUCTURE OF PHOTOLYASE

PDB ID 1qnf

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1qnf"
Personal tools