1zk1

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{{Seed}}
 
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[[Image:1zk1.png|left|200px]]
 
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==Structure of R-specific alcohol dehydrogenase (mutant G37D) from Lactobacillus brevis in complex with phenylethanol and NAD==
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The line below this paragraph, containing "STRUCTURE_1zk1", creates the "Structure Box" on the page.
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<StructureSection load='1zk1' size='340' side='right'caption='[[1zk1]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1zk1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Levilactobacillus_brevis Levilactobacillus brevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZK1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZK1 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.78&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AC0:1-PHENYLETHANONE'>AC0</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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{{STRUCTURE_1zk1| PDB=1zk1 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zk1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zk1 OCA], [https://pdbe.org/1zk1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zk1 RCSB], [https://www.ebi.ac.uk/pdbsum/1zk1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zk1 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q84EX5_LEVBR Q84EX5_LEVBR]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zk/1zk1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zk1 ConSurf].
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<div style="clear:both"></div>
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===Structure of R-specific alcohol dehydrogenase (mutant G37D) from Lactobacillus brevis in complex with phenylethanol and NAD===
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==See Also==
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*[[Alcohol dehydrogenase 3D structures|Alcohol dehydrogenase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_15896805}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 15896805 is the PubMed ID number.
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[[Category: Levilactobacillus brevis]]
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[[Category: Hummel W]]
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{{ABSTRACT_PUBMED_15896805}}
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[[Category: Muller J]]
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[[Category: Niefind K]]
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==About this Structure==
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[[Category: Riebel B]]
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1ZK1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Lactobacillus_brevis Lactobacillus brevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZK1 OCA].
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[[Category: Schlieben NH]]
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[[Category: Schomburg D]]
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==Reference==
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Atomic resolution structures of R-specific alcohol dehydrogenase from Lactobacillus brevis provide the structural bases of its substrate and cosubstrate specificity., Schlieben NH, Niefind K, Muller J, Riebel B, Hummel W, Schomburg D, J Mol Biol. 2005 Jun 17;349(4):801-13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15896805 15896805]
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The crystal structure of R-specific alcohol dehydrogenase from Lactobacillus brevis suggests the structural basis of its metal dependency., Niefind K, Muller J, Riebel B, Hummel W, Schomburg D, J Mol Biol. 2003 Mar 21;327(2):317-28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12628239 12628239]
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Crystallization and preliminary characterization of crystals of R-alcohol dehydrogenase from Lactobacillus brevis., Niefind K, Riebel B, Muller J, Hummel W, Schomburg D, Acta Crystallogr D Biol Crystallogr. 2000 Dec;56(Pt 12):1696-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11092950 11092950]
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[[Category: Lactobacillus brevis]]
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[[Category: Single protein]]
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[[Category: Hummel, W.]]
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[[Category: Muller, J.]]
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[[Category: Niefind, K.]]
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[[Category: Riebel, B.]]
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[[Category: Schlieben, N H.]]
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[[Category: Schomburg, D.]]
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[[Category: Magnesium dependence]]
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[[Category: R-specific alcohol dehydrogenase]]
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[[Category: Short chain reductases/dehydrogenase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 16:33:23 2008''
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Current revision

Structure of R-specific alcohol dehydrogenase (mutant G37D) from Lactobacillus brevis in complex with phenylethanol and NAD

PDB ID 1zk1

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