1wai
From Proteopedia
(Difference between revisions)
| (9 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | + | {{Theoretical_model}} | |
| - | + | ==DNA POLYMERASE FROM BACTERIOPHAGE RB69, ALPHA-CARBONS ONLY, WITH DNA MODELED IN THE POLYMERASE ACTIVE SITE, THEORETICAL MODEL== | |
| + | <StructureSection load='1wai' size='340' side='right'caption='[[1wai]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WAI FirstGlance]. <br> | ||
| + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wai FirstGlance], [https://www.ebi.ac.uk/pdbsum/1wai PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wai ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The 2.8 A resolution crystal structure of the bacteriophage RB69 gp43, a member of the eukaryotic pol alpha family of replicative DNA polymerases, shares some similarities with other polymerases but shows many differences. Although its palm domain has the same topology as other polymerases, except rat DNA polymerase beta, one of the three carboxylates required for nucleotidyl transfer is located on a different beta strand. The structures of the fingers and thumb domains are unrelated to all other known polymerase structures. The editing 3'-5' exonuclease domain of gp43 is homologous to that of E. coli DNA polymerase I but lies on the opposite side of the polymerase active site. An extended structure-based alignment of eukaryotic DNA polymerase sequences provides structural insights that should be applicable to most eukaryotic DNA polymerases. | ||
| - | + | Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69.,Wang J, Sattar AK, Wang CC, Karam JD, Konigsberg WH, Steitz TA Cell. 1997 Jun 27;89(7):1087-99. PMID:9215631<ref>PMID:9215631</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| + | <div class="pdbe-citations 1wai" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Theoretical Model]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Karam, J D]] | ||
| + | [[Category: Konigsberg, W H]] | ||
| + | [[Category: Satter, A K.M A]] | ||
| + | [[Category: Steitz, T A]] | ||
| + | [[Category: Wang, C C]] | ||
| + | [[Category: Wang, J]] | ||
Current revision
 |
DNA POLYMERASE FROM BACTERIOPHAGE RB69, ALPHA-CARBONS ONLY, WITH DNA MODELED IN THE POLYMERASE ACTIVE SITE, THEORETICAL MODEL
| |||||||||||
