3dhx

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{{Seed}}
 
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[[Image:3dhx.jpg|left|200px]]
 
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==Crystal structure of isolated C2 domain of the methionine uptake transporter==
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The line below this paragraph, containing "STRUCTURE_3dhx", creates the "Structure Box" on the page.
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<StructureSection load='3dhx' size='340' side='right'caption='[[3dhx]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3dhx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DHX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DHX FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
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{{STRUCTURE_3dhx| PDB=3dhx | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dhx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dhx OCA], [https://pdbe.org/3dhx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dhx RCSB], [https://www.ebi.ac.uk/pdbsum/3dhx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dhx ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/METN_ECOLI METN_ECOLI] Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (Probable). It has also been shown to be involved in formyl-L-methionine transport.<ref>PMID:12169620</ref> <ref>PMID:12819857</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dh/3dhx_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dhx ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of isolated C2 domain of the methionine uptake transporter===
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==See Also==
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*[[ABC transporter 3D structures|ABC transporter 3D structures]]
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 18621668 is the PubMed ID number.
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</StructureSection>
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[[Category: Escherichia coli K-12]]
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{{ABSTRACT_PUBMED_18621668}}
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[[Category: Large Structures]]
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[[Category: Johnson E]]
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==About this Structure==
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[[Category: Kaiser JT]]
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3DHX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k12 Escherichia coli k12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DHX OCA].
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[[Category: Lee AT]]
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[[Category: Rees DC]]
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==Reference==
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The high-affinity E. coli methionine ABC transporter: structure and allosteric regulation., Kadaba NS, Kaiser JT, Johnson E, Lee A, Rees DC, Science. 2008 Jul 11;321(5886):250-3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18621668 18621668]
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[[Category: Escherichia coli k12]]
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[[Category: Single protein]]
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[[Category: Johnson, E.]]
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[[Category: Kaiser, J T.]]
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[[Category: Lee, A T.]]
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[[Category: Rees, D C.]]
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[[Category: Amino-acid transport]]
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[[Category: Atp-binding]]
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[[Category: Hydrolase]]
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[[Category: Inner membrane]]
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[[Category: Membrane]]
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[[Category: Methionine uptake]]
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[[Category: Nucleotide-binding]]
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[[Category: Regulation]]
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[[Category: Transport]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 6 13:05:19 2008''
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Current revision

Crystal structure of isolated C2 domain of the methionine uptake transporter

PDB ID 3dhx

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