This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3e2i
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3e2i is ON HOLD until Paper Publication Authors: Lam, R., Johns, K., Battaile, K.P., Romanov, V., Lam, K., Pai, E.F., Chirgadze, N.Y. Description: ...) |
|||
| (8 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Thymidine Kinase from S. aureus== | |
| + | <StructureSection load='3e2i' size='340' side='right'caption='[[3e2i]], [[Resolution|resolution]] 2.01Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3e2i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E2I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E2I FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tdk ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Thymidine_kinase Thymidine kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.21 2.7.1.21] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e2i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e2i OCA], [https://pdbe.org/3e2i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e2i RCSB], [https://www.ebi.ac.uk/pdbsum/3e2i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e2i ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e2/3e2i_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3e2i ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| - | + | *[[Thymidine kinase|Thymidine kinase]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| + | [[Category: Thymidine kinase]] | ||
| + | [[Category: Battaile, K P]] | ||
| + | [[Category: Chirgadze, N Y]] | ||
| + | [[Category: Johns, K]] | ||
| + | [[Category: Lam, K]] | ||
| + | [[Category: Lam, R]] | ||
| + | [[Category: Pai, E F]] | ||
| + | [[Category: Romanov, V]] | ||
| + | [[Category: Atp-binding]] | ||
| + | [[Category: Dna synthesis]] | ||
| + | [[Category: Kinase]] | ||
| + | [[Category: Nucleotide-binding]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Zn-binding]] | ||
Current revision
Crystal structure of Thymidine Kinase from S. aureus
| |||||||||||
Categories: Large Structures | Thymidine kinase | Battaile, K P | Chirgadze, N Y | Johns, K | Lam, K | Lam, R | Pai, E F | Romanov, V | Atp-binding | Dna synthesis | Kinase | Nucleotide-binding | Transferase | Zn-binding
