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3dwu

From Proteopedia

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{{Seed}}
 
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[[Image:3dwu.jpg|left|200px]]
 
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==Transition-state model conformation of the switch I region fitted into the cryo-EM map of the eEF2.80S.AlF4.GDP complex==
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The line below this paragraph, containing "STRUCTURE_3dwu", creates the "Structure Box" on the page.
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<SX load='3dwu' size='340' side='right' viewer='molstar' caption='[[3dwu]], [[Resolution|resolution]] 12.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3dwu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DWU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DWU FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 12.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dwu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dwu OCA], [https://pdbe.org/3dwu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dwu RCSB], [https://www.ebi.ac.uk/pdbsum/3dwu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dwu ProSAT]</span></td></tr>
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{{STRUCTURE_3dwu| PDB=3dwu | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/EFTU2_THET8 EFTU2_THET8] This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dw/3dwu_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dwu ConSurf].
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<div style="clear:both"></div>
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===Transition-state model conformation of the switch I region fitted into the cryo-EM map of the eEF2.80S.AlF4.GDP complex===
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==See Also==
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*[[Elongation factor 3D structures|Elongation factor 3D structures]]
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__TOC__
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</SX>
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The line below this paragraph, {{ABSTRACT_PUBMED_18644383}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 18644383 is the PubMed ID number.
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[[Category: Thermus thermophilus HB8]]
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[[Category: Kjeldgaard M]]
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{{ABSTRACT_PUBMED_18644383}}
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[[Category: Nissen P]]
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[[Category: Nyborg J]]
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==About this Structure==
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3DWU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DWU OCA].
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==Reference==
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Visualization of the eEF2-80S Ribosome Transition-State Complex by Cryo-Electron Microscopy., Sengupta J, Nilsson J, Gursky R, Kjeldgaard M, Nissen P, Frank J, J Mol Biol. 2008 Jul 11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18644383 18644383]
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[[Category: Single protein]]
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[[Category: Thermus thermophilus hb8]]
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[[Category: Kjeldgaard, M.]]
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[[Category: Nissen, P.]]
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[[Category: Nyborg, J.]]
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[[Category: Acetylation]]
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[[Category: Antibiotic resistance]]
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[[Category: Biosynthetic protein]]
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[[Category: Conserved switch i]]
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[[Category: Cytoplasm]]
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[[Category: Elongation factor]]
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[[Category: Gtp-binding]]
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[[Category: Membrane]]
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[[Category: Methylation]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Protein biosynthesis]]
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[[Category: Transition state]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 13 13:50:07 2008''
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Current revision

Transition-state model conformation of the switch I region fitted into the cryo-EM map of the eEF2.80S.AlF4.GDP complex

3dwu, resolution 12.60Å

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