2r2k

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:36, 30 October 2024) (edit) (undo)
 
(11 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2r2k.png|left|200px]]
 
-
<!--
+
==Crystal structure of the complex of camel peptidoglycan recognition protein with disaccharide at 3.2A resolution==
-
The line below this paragraph, containing "STRUCTURE_2r2k", creates the "Structure Box" on the page.
+
<StructureSection load='2r2k' size='340' side='right'caption='[[2r2k]], [[Resolution|resolution]] 3.25&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2r2k]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R2K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R2K FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.25&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
-
{{STRUCTURE_2r2k| PDB=2r2k | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r2k OCA], [https://pdbe.org/2r2k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r2k RCSB], [https://www.ebi.ac.uk/pdbsum/2r2k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r2k ProSAT]</span></td></tr>
-
 
+
</table>
-
===Crystal structure of the complex of camel peptidoglycan recognition protein with disaccharide at 3.2A resolution===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/PGRP1_CAMDR PGRP1_CAMDR] Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. Is microbicidal for Gram-positive and Gram-negative bacteria and yeast. May function in intracellular killing of bacteria (By similarity).
-
 
+
== Evolutionary Conservation ==
-
==About this Structure==
+
[[Image:Consurf_key_small.gif|200px|right]]
-
2R2K is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R2K OCA].
+
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r2/2r2k_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r2k ConSurf].
 +
<div style="clear:both"></div>
 +
__TOC__
 +
</StructureSection>
[[Category: Camelus dromedarius]]
[[Category: Camelus dromedarius]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Bhushan, A.]]
+
[[Category: Bhushan A]]
-
[[Category: Jain, R.]]
+
[[Category: Jain R]]
-
[[Category: Kaur, P.]]
+
[[Category: Kaur P]]
-
[[Category: Sharma, P.]]
+
[[Category: Sharma P]]
-
[[Category: Sharma, S.]]
+
[[Category: Sharma S]]
-
[[Category: Singh, N.]]
+
[[Category: Singh N]]
-
[[Category: Singh, T P.]]
+
[[Category: Singh TP]]
-
[[Category: Antibiotic]]
+
-
[[Category: Antimicrobial]]
+
-
[[Category: Complex]]
+
-
[[Category: Disaccharide]]
+
-
[[Category: Immune response]]
+
-
[[Category: Peptidoglycan recognition protein]]
+
-
[[Category: Secreted]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 27 10:42:03 2008''
+

Current revision

Crystal structure of the complex of camel peptidoglycan recognition protein with disaccharide at 3.2A resolution

PDB ID 2r2k

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2r2k"
Personal tools