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3d8n

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{{Seed}}
 
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[[Image:3d8n.png|left|200px]]
 
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<!--
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==Uroporphyrinogen III Synthase-Uroporphyringen III Complex==
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The line below this paragraph, containing "STRUCTURE_3d8n", creates the "Structure Box" on the page.
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<StructureSection load='3d8n' size='340' side='right'caption='[[3d8n]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3d8n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB27 Thermus thermophilus HB27]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D8N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D8N FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UP3:3,3,3,3-[3,8,13,17-TETRAKIS(CARBOXYMETHYL)PORPHYRIN-2,7,12,18-TETRAYL]TETRAPROPANOIC+ACID'>UP3</scene></td></tr>
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{{STRUCTURE_3d8n| PDB=3d8n | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d8n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d8n OCA], [https://pdbe.org/3d8n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d8n RCSB], [https://www.ebi.ac.uk/pdbsum/3d8n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d8n ProSAT]</span></td></tr>
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</table>
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===Uroporphyrinogen III Synthase-Uroporphyringen III Complex===
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== Function ==
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[https://www.uniprot.org/uniprot/Q72KM1_THET2 Q72KM1_THET2]
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_18651750}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 18651750 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d8/3d8n_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_18651750}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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3D8N is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb27 Thermus thermophilus hb27]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D8N OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3d8n ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Structure and Mechanistic Implications of a Uroporphyrinogen III Synthase-Product Complex., Schubert HL, Phillips JD, Heroux A, Hill CP, Biochemistry. 2008 Jul 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18651750 18651750]
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</StructureSection>
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Thermus thermophilus hb27]]
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[[Category: Thermus thermophilus HB27]]
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[[Category: Uroporphyrinogen-III synthase]]
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[[Category: Schubert HL]]
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[[Category: Schubert, H L.]]
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[[Category: Heme biosynthesis]]
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[[Category: Lyase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 27 10:42:41 2008''
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Current revision

Uroporphyrinogen III Synthase-Uroporphyringen III Complex

PDB ID 3d8n

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