3e8y
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3e8y is ON HOLD Authors: Kalyaneswar Mandal, Brad L. Pentelute, Valentina Tereshko, Anthony A. Kossiakoff, Stephen B. H. Kent Description: Xray str...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Xray structure of scorpion toxin BmBKTx1== | |
| + | <StructureSection load='3e8y' size='340' side='right'caption='[[3e8y]], [[Resolution|resolution]] 1.10Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3e8y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mesobuthus_martensii Mesobuthus martensii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E8Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E8Y FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e8y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e8y OCA], [https://pdbe.org/3e8y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e8y RCSB], [https://www.ebi.ac.uk/pdbsum/3e8y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e8y ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/KA191_MESMA KA191_MESMA] Selective inhibitor of high conductance calcium-activated potassium channels KCa1.1/KCNMA1. May be insect specific.<ref>PMID:15178692</ref> [PDB:3E8Y] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Racemic protein crystallography, enabled by total chemical synthesis, has allowed us to determine the X-ray structure of native scorpion toxin BmBKTx1; direct methods were used for phase determination. This is the first example of a protein racemate that crystallized in space group I41/a. | ||
| - | + | X-ray structure of native scorpion toxin BmBKTx1 by racemic protein crystallography using direct methods.,Mandal K, Pentelute BL, Tereshko V, Kossiakoff AA, Kent SB J Am Chem Soc. 2009 Feb 4;131(4):1362-3. PMID:19133782<ref>PMID:19133782</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| + | </div> | ||
| + | <div class="pdbe-citations 3e8y" style="background-color:#fffaf0;"></div> | ||
| - | + | ==See Also== | |
| + | *[[Potassium channel toxin 3D structures|Potassium channel toxin 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mesobuthus martensii]] | ||
| + | [[Category: Kent SBH]] | ||
| + | [[Category: Kossiakoff AA]] | ||
| + | [[Category: Mandal K]] | ||
| + | [[Category: Pentelute BL]] | ||
| + | [[Category: Tereshko V]] | ||
Current revision
Xray structure of scorpion toxin BmBKTx1
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