3d3k

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{{Seed}}
 
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[[Image:3d3k.jpg|left|200px]]
 
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==Crystal structure of human Edc3p==
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The line below this paragraph, containing "STRUCTURE_3d3k", creates the "Structure Box" on the page.
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<StructureSection load='3d3k' size='340' side='right'caption='[[3d3k]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3d3k]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D3K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D3K FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d3k OCA], [https://pdbe.org/3d3k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d3k RCSB], [https://www.ebi.ac.uk/pdbsum/3d3k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d3k ProSAT]</span></td></tr>
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{{STRUCTURE_3d3k| PDB=3d3k | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of human Edc3p===
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[https://www.uniprot.org/uniprot/EDC3_HUMAN EDC3_HUMAN] Binds single-stranded RNA. In the process of mRNA degradation, may play a role in mRNA decapping. May play a role in spermiogenesis and oogenesis.<ref>PMID:16364915</ref> <ref>PMID:17533573</ref> <ref>PMID:18678652</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 18678652 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d3/3d3k_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_18678652}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3d3k ConSurf].
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3D3K is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D3K OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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Crystal structure of human Edc3 and its functional implications., Ling SH, Decker CJ, Walsh MA, She M, Parker R, Song H, Mol Cell Biol. 2008 Aug 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18678652 18678652]
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Ling, S H.M.]]
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[[Category: Ling SHM]]
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[[Category: Cytoplasm]]
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[[Category: Hedc3]]
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[[Category: Phosphoprotein]]
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[[Category: Protein binding]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 27 11:27:42 2008''
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Current revision

Crystal structure of human Edc3p

PDB ID 3d3k

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