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3dlh

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{{Seed}}
 
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[[Image:3dlh.jpg|left|200px]]
 
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==Crystal structure of the guide-strand-containing Argonaute protein silencing complex==
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The line below this paragraph, containing "STRUCTURE_3dlh", creates the "Structure Box" on the page.
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<StructureSection load='3dlh' size='340' side='right'caption='[[3dlh]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3dlh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB27 Thermus thermophilus HB27]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DLH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DLH FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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{{STRUCTURE_3dlh| PDB=3dlh | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dlh OCA], [https://pdbe.org/3dlh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dlh RCSB], [https://www.ebi.ac.uk/pdbsum/3dlh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dlh ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q746M7_THET2 Q746M7_THET2]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dl/3dlh_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dlh ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of the guide-strand-containing Argonaute protein silencing complex===
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==See Also==
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*[[Argonaute 3D structures|Argonaute 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_18754009}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 18754009 is the PubMed ID number.
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[[Category: Thermus thermophilus HB27]]
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[[Category: Patel DJ]]
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{{ABSTRACT_PUBMED_18754009}}
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[[Category: Sheng G]]
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[[Category: Wang Y]]
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==About this Structure==
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3DLH is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DLH OCA].
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==Reference==
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Structure of the guide-strand-containing argonaute silencing complex., Wang Y, Sheng G, Juranek S, Tuschl T, Patel DJ, Nature. 2008 Aug 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18754009 18754009]
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[[Category: Protein complex]]
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[[Category: Thermus thermophilus]]
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[[Category: Patel, D J.]]
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[[Category: Sheng, G.]]
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[[Category: Wang, Y.]]
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[[Category: Argonaute]]
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[[Category: Nucleic acid binding protein/dna complex]]
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[[Category: Plasmid]]
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[[Category: Protein-dna complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 10 09:11:42 2008''
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Current revision

Crystal structure of the guide-strand-containing Argonaute protein silencing complex

PDB ID 3dlh

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