We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

2nv4

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:43, 9 October 2024) (edit) (undo)
 
(11 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2nv4.png|left|200px]]
 
-
<!--
+
==Crystal structure of UPF0066 protein AF0241 in complex with S-adenosylmethionine. Northeast Structural Genomics Consortium target GR27==
-
The line below this paragraph, containing "STRUCTURE_2nv4", creates the "Structure Box" on the page.
+
<StructureSection load='2nv4' size='340' side='right'caption='[[2nv4]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2nv4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NV4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NV4 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
-
{{STRUCTURE_2nv4| PDB=2nv4 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nv4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nv4 OCA], [https://pdbe.org/2nv4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nv4 RCSB], [https://www.ebi.ac.uk/pdbsum/2nv4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nv4 ProSAT], [https://www.topsan.org/Proteins/NESGC/2nv4 TOPSAN]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Y241_ARCFU Y241_ARCFU]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nv/2nv4_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2nv4 ConSurf].
 +
<div style="clear:both"></div>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
Structural genomics efforts have produced structural information, either directly or by modeling, for thousands of proteins over the past few years. While many of these proteins have known functions, a large percentage of them have not been characterized at the functional level. The structural information has provided valuable functional insights on some of these proteins, through careful structural analyses, serendipity, and structure-guided functional screening. Some of the success stories based on structures solved at the Northeast Structural Genomics Consortium (NESG) are reported here. These include a novel methyl salicylate esterase with important role in plant innate immunity, a novel RNA methyltransferase (H. influenzae yggJ (HI0303)), a novel spermidine/spermine N-acetyltransferase (B. subtilis PaiA), a novel methyltransferase or AdoMet binding protein (A. fulgidus AF_0241), an ATP:cob(I)alamin adenosyltransferase (B. subtilis YvqK), a novel carboxysome pore (E. coli EutN), a proline racemase homolog with a disrupted active site (B. melitensis BME11586), an FMN-dependent enzyme (S. pneumoniae SP_1951), and a 12-stranded beta-barrel with a novel fold (V. parahaemolyticus VPA1032).
-
===Crystal structure of UPF0066 protein AF0241 in complex with S-adenosylmethionine. Northeast Structural Genomics Consortium target GR27===
+
Functional insights from structural genomics.,Forouhar F, Kuzin A, Seetharaman J, Lee I, Zhou W, Abashidze M, Chen Y, Yong W, Janjua H, Fang Y, Wang D, Cunningham K, Xiao R, Acton TB, Pichersky E, Klessig DF, Porter CW, Montelione GT, Tong L J Struct Funct Genomics. 2007 Sep;8(2-3):37-44. Epub 2007 Jun 23. PMID:17588214<ref>PMID:17588214</ref>
-
 
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
<!--
+
</div>
-
The line below this paragraph, {{ABSTRACT_PUBMED_17588214}}, adds the Publication Abstract to the page
+
<div class="pdbe-citations 2nv4" style="background-color:#fffaf0;"></div>
-
(as it appears on PubMed at http://www.pubmed.gov), where 17588214 is the PubMed ID number.
+
== References ==
-
-->
+
<references/>
-
{{ABSTRACT_PUBMED_17588214}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
-
2NV4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NV4 OCA].
+
-
 
+
-
==Reference==
+
-
Functional insights from structural genomics., Forouhar F, Kuzin A, Seetharaman J, Lee I, Zhou W, Abashidze M, Chen Y, Yong W, Janjua H, Fang Y, Wang D, Cunningham K, Xiao R, Acton TB, Pichersky E, Klessig DF, Porter CW, Montelione GT, Tong L, J Struct Funct Genomics. 2007 Sep;8(2-3):37-44. Epub 2007 Jun 23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17588214 17588214]
+
[[Category: Archaeoglobus fulgidus]]
[[Category: Archaeoglobus fulgidus]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Abashidze, M.]]
+
[[Category: Abashidze M]]
-
[[Category: Acton, T B.]]
+
[[Category: Acton TB]]
-
[[Category: Baran, M.]]
+
[[Category: Baran M]]
-
[[Category: Cunningham, K.]]
+
[[Category: Cunningham K]]
-
[[Category: Fang, Y.]]
+
[[Category: Fang Y]]
-
[[Category: Hunt, J F.]]
+
[[Category: Hunt JF]]
-
[[Category: Kuzin, A P.]]
+
[[Category: Kuzin AP]]
-
[[Category: Liu, J.]]
+
[[Category: Liu J]]
-
[[Category: Ma, L C.]]
+
[[Category: Ma LC]]
-
[[Category: Montelione, G T.]]
+
[[Category: Montelione GT]]
-
[[Category: NESG, Northeast Structural Genomics Consortium.]]
+
[[Category: Rost B]]
-
[[Category: Rost, B.]]
+
[[Category: Seetharaman J]]
-
[[Category: Seetharaman, J.]]
+
[[Category: Tong L]]
-
[[Category: Tong, L.]]
+
[[Category: Vorobiev SM]]
-
[[Category: Vorobiev, S M.]]
+
[[Category: Xiao R]]
-
[[Category: Xiao, R.]]
+
-
[[Category: Nesg gr27 y241_arcfu x-ray]]
+
-
[[Category: Northeast structural genomics consortium]]
+
-
[[Category: Protein structure initiative]]
+
-
[[Category: Psi-2]]
+
-
[[Category: Structural genomic]]
+
-
[[Category: Unknown function]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 17 12:55:37 2008''
+

Current revision

Crystal structure of UPF0066 protein AF0241 in complex with S-adenosylmethionine. Northeast Structural Genomics Consortium target GR27

PDB ID 2nv4

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2nv4"
Personal tools