2v9z
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:2v9z.jpg|left|200px]] | ||
| - | < | + | ==Structure of the Rhodococcus haloalkane dehalogenase mutant with enhanced enantioselectivity== |
| - | + | <StructureSection load='2v9z' size='340' side='right'caption='[[2v9z]], [[Resolution|resolution]] 3.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2v9z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_rhodochrous Rhodococcus rhodochrous]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V9Z FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr> | |
| - | --> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v9z OCA], [https://pdbe.org/2v9z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v9z RCSB], [https://www.ebi.ac.uk/pdbsum/2v9z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v9z ProSAT]</span></td></tr> |
| - | + | </table> | |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DHAA_RHORH DHAA_RHORH] Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Expresses halogenase activity against 1-chloroalkanes of chain length C3 to C10, and also shows a very weak activity with 1,2-dichloroethane. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v9/2v9z_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2v9z ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Dehalogenase 3D structures|Dehalogenase 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| - | [[Category: | + | |
[[Category: Rhodococcus rhodochrous]] | [[Category: Rhodococcus rhodochrous]] | ||
| - | + | [[Category: Chovancova E]] | |
| - | [[Category: Chovancova | + | [[Category: Damborsky J]] |
| - | [[Category: Damborsky | + | [[Category: Emmer J]] |
| - | [[Category: Emmer | + | [[Category: Jesenska A]] |
| - | [[Category: Jesenska | + | [[Category: Koudelakova T]] |
| - | [[Category: Koudelakova | + | [[Category: Kuta Smatanova I]] |
| - | [[Category: Lapkouski | + | [[Category: Lapkouski M]] |
| - | [[Category: Monincova | + | [[Category: Monincova M]] |
| - | [[Category: Nagata | + | [[Category: Nagata Y]] |
| - | [[Category: Prokop | + | [[Category: Prokop Z]] |
| - | [[Category: Sato | + | [[Category: Sato Y]] |
| - | [[Category: Senda | + | [[Category: Senda T]] |
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Current revision
Structure of the Rhodococcus haloalkane dehalogenase mutant with enhanced enantioselectivity
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