1ri7

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(New page: 200px<br /><applet load="1ri7" size="450" color="white" frame="true" align="right" spinBox="true" caption="1ri7, resolution 2.7&Aring;" /> '''crystal structure of ...)
Current revision (13:29, 13 March 2024) (edit) (undo)
 
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[[Image:1ri7.jpg|left|200px]]<br /><applet load="1ri7" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1ri7, resolution 2.7&Aring;" />
 
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'''crystal structure of a protein in the LRP/ASNC family from the hyperthermophilic archaeon Pyrococcus sp. OT3'''<br />
 
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==Overview==
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==crystal structure of a protein in the LRP/ASNC family from the hyperthermophilic archaeon Pyrococcus sp. OT3==
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The classification feast/famine regulatory proteins (FFRPs) encompasses, archaeal DNA-binding proteins with Escherichia coli transcription factors, the leucine-responsive regulatory protein and the asparagine synthase C, gene product. In this paper, we describe two forms of the archaeal FFRP, FL11 (pot0434017), both assembled from dimers. When crystallized, a, helical cylinder is formed with six dimers per turn. In contrast, in, solution, disks are formed, most likely consisting of four dimers each; an, observation by cryoelectron microscopy. Whereas each dimer binds a 13-bp, sequence, different forms will discriminate between promoters, based on, the numbers of repeating 13-bp sequences, and types of linkers inserted, between them, which are either of 7-8 or approximately 18 bp. The amino, acid sequences of these FFRPs are designed to form the same type of 3D, structures, and the transition between their assembly forms is regulated, by interaction with small molecules. These considerations lead us to, propose a possible mechanism for regulating a number of genes by varying, assembly forms and by combining different FFRPs into these assemblies, responding to environmental changes.
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<StructureSection load='1ri7' size='340' side='right'caption='[[1ri7]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[1ri7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RI7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RI7 FirstGlance]. <br>
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1RI7 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Paracoccus_sp. Paracoccus sp.]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1RI7 OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ri7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ri7 OCA], [https://pdbe.org/1ri7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ri7 RCSB], [https://www.ebi.ac.uk/pdbsum/1ri7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ri7 ProSAT]</span></td></tr>
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==Reference==
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</table>
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The archaeal feast/famine regulatory protein: potential roles of its assembly forms for regulating transcription., Koike H, Ishijima SA, Clowney L, Suzuki M, Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):2840-5. Epub 2004 Feb 19. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14976242 14976242]
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== Function ==
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[[Category: Paracoccus sp.]]
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[https://www.uniprot.org/uniprot/REG6_PYRHO REG6_PYRHO]
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[[Category: Single protein]]
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== Evolutionary Conservation ==
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[[Category: Koike, H.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Suzuki, M.]]
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Check<jmol>
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[[Category: lrp/asnc family]]
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<jmolCheckbox>
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[[Category: transcription]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ri/1ri7_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 01:37:10 2007''
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ri7 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Pyrococcus horikoshii OT3]]
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[[Category: Koike H]]
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[[Category: Suzuki M]]

Current revision

crystal structure of a protein in the LRP/ASNC family from the hyperthermophilic archaeon Pyrococcus sp. OT3

PDB ID 1ri7

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