1why

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{{Seed}}
 
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[[Image:1why.png|left|200px]]
 
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==Solution structure of the RNA recognition motif from hypothetical RNA binding protein BC052180==
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The line below this paragraph, containing "STRUCTURE_1why", creates the "Structure Box" on the page.
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<StructureSection load='1why' size='340' side='right'caption='[[1why]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1why]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WHY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WHY FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1why FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1why OCA], [https://pdbe.org/1why PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1why RCSB], [https://www.ebi.ac.uk/pdbsum/1why PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1why ProSAT], [https://www.topsan.org/Proteins/RSGI/1why TOPSAN]</span></td></tr>
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{{STRUCTURE_1why| PDB=1why | SCENE= }}
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</table>
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== Function ==
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===Solution structure of the RNA recognition motif from hypothetical RNA binding protein BC052180===
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[https://www.uniprot.org/uniprot/RB15B_MOUSE RB15B_MOUSE] RNA-binding protein that acts as a key regulator of N6-methyladenosine (m6A) methylation of RNAs, thereby regulating different processes, such as alternative splicing of mRNAs and X chromosome inactivation mediated by Xist RNA. Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Plays a key role in m6A methylation, possibly by binding target RNAs and recruiting the WMM complex. Involved in random X inactivation mediated by Xist RNA: acts by binding Xist RNA and recruiting the WMM complex, which mediates m6A methylation, leading to target YTHDC1 reader on Xist RNA and promoting transcription repression activity of Xist. Functions in the regulation of alternative or illicit splicing, possibly by regulating m6A methylation. Inhibits pre-mRNA splicing. Also functions as a mRNA export factor by acting as a cofactor for the nuclear export receptor NXF1.[UniProtKB:Q8NDT2]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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1WHY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WHY OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wh/1why_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1why ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Single protein]]
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[[Category: Inoue M]]
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[[Category: Inoue, M.]]
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[[Category: Kigawa T]]
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[[Category: Kigawa, T.]]
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[[Category: Muto Y]]
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[[Category: Muto, Y.]]
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[[Category: Nagata T]]
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[[Category: Nagata, T.]]
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[[Category: Shirouzu M]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Terada T]]
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[[Category: Shirouzu, M.]]
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[[Category: Yokoyama S]]
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[[Category: Terada, T.]]
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[[Category: Yokoyama, S.]]
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[[Category: Rbd]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rna binding domain]]
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[[Category: Rna recognition motif]]
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[[Category: Rnp]]
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[[Category: Rrm]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Sep 28 19:01:58 2008''
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Current revision

Solution structure of the RNA recognition motif from hypothetical RNA binding protein BC052180

PDB ID 1why

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Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1why"
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