3cni

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{{Seed}}
 
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[[Image:3cni.png|left|200px]]
 
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==Crystal structure of a domain of a putative ABC type-2 transporter from Thermotoga maritima MSB8==
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The line below this paragraph, containing "STRUCTURE_3cni", creates the "Structure Box" on the page.
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<StructureSection load='3cni' size='340' side='right'caption='[[3cni]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3cni]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thema Thema]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CNI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CNI FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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{{STRUCTURE_3cni| PDB=3cni | SCENE= }}
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TM_0543 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243274 THEMA])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cni FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cni OCA], [https://pdbe.org/3cni PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cni RCSB], [https://www.ebi.ac.uk/pdbsum/3cni PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cni ProSAT], [https://www.topsan.org/Proteins/MCSG/3cni TOPSAN]</span></td></tr>
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</table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cn/3cni_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cni ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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This study describes the structure of the putative ABC-type 2 transporter TM0543 from Thermotoga maritima MSB8 determined at a resolution of 2.3 A. In comparative sequence-clustering analysis, TM0543 displays similarity to NatAB-like proteins, which are components of the ABC-type Na+ efflux pump permease. However, the overall structure fold of the predicted nucleotide-binding domain reveals that it is different from any known structure of ABC-type efflux transporters solved to date. The structure of the putative TM0543 domain also exhibits different dimer architecture and topology of its presumed ATP binding pocket, which may indicate that it does not bind nucleotide at all. Structural analysis of calcium ion binding sites found at the interface between TM0543 dimer subunits suggests that protein may be involved in ion-transporting activity. A detailed analysis of the protein sequence and structure is presented and discussed.
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===Crystal structure of a domain of a putative ABC type-2 transporter from Thermotoga maritima MSB8===
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Structural characterization of the putative ABC-type 2 transporter from Thermotoga maritima MSB8.,Filippova EV, Tkaczuk KL, Chruszcz M, Xu X, Savchenko A, Edwards A, Minor W J Struct Funct Genomics. 2014 Oct 12. PMID:25306867<ref>PMID:25306867</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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==About this Structure==
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</div>
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3CNI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CNI OCA].
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<div class="pdbe-citations 3cni" style="background-color:#fffaf0;"></div>
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[[Category: Single protein]]
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== References ==
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[[Category: Thermotoga maritima msb8]]
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<references/>
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[[Category: Chruszcz, M.]]
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__TOC__
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[[Category: Cymborowski, M.]]
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</StructureSection>
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[[Category: Edwards, A M.]]
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[[Category: Large Structures]]
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[[Category: Filippova, E.]]
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[[Category: Thema]]
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[[Category: Joachimiak, A.]]
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[[Category: Chruszcz, M]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Cymborowski, M]]
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[[Category: Minor, W.]]
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[[Category: Edwards, A M]]
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[[Category: Que, Q.]]
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[[Category: Filippova, E V]]
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[[Category: Savchenko, A.]]
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[[Category: Joachimiak, A]]
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[[Category: Shumilin, I.]]
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[[Category: Structural genomic]]
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[[Category: Tkaczuk, K.]]
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[[Category: Minor, W]]
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[[Category: Xu, X.]]
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[[Category: Que, Q]]
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[[Category: Savchenko, A]]
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[[Category: Shumilin, I]]
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[[Category: Tkaczuk, K L]]
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[[Category: Xu, X]]
[[Category: Abc type-2 transporter]]
[[Category: Abc type-2 transporter]]
[[Category: Mcsg]]
[[Category: Mcsg]]
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[[Category: Midwest center for structural genomic]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-2]]
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[[Category: Structural genomic]]
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[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
[[Category: Transport protein]]
[[Category: Transport protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Sep 28 19:28:57 2008''
 

Current revision

Crystal structure of a domain of a putative ABC type-2 transporter from Thermotoga maritima MSB8

PDB ID 3cni

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OCA

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