2gk3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:04, 30 October 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2gk3.png|left|200px]]
 
-
<!--
+
==Cytoplasmic Protein STM3548 from Salmonella typhimurium==
-
The line below this paragraph, containing "STRUCTURE_2gk3", creates the "Structure Box" on the page.
+
<StructureSection load='2gk3' size='340' side='right'caption='[[2gk3]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2gk3]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GK3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GK3 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-
{{STRUCTURE_2gk3| PDB=2gk3 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gk3 OCA], [https://pdbe.org/2gk3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gk3 RCSB], [https://www.ebi.ac.uk/pdbsum/2gk3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gk3 ProSAT], [https://www.topsan.org/Proteins/MCSG/2gk3 TOPSAN]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q8ZLF9_SALTY Q8ZLF9_SALTY]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gk/2gk3_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gk3 ConSurf].
 +
<div style="clear:both"></div>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
The cytoplasmic protein Stm3548 of unknown function obtained from a strain of Salmonella typhimurium was determined by X-ray crystallography at a resolution of 2.25 A. The asymmetric unit contains a hexamer of structurally identical monomers. The monomer is a globular domain with a long beta-hairpin protrusion that distinguishes this structure. This beta-hairpin occupies a central position in the hexamer, and its residues participate in the majority of interactions between subunits of the hexamer. We suggest that the structure of Stm3548 presents a new hexamerization motif. Because the residues participating in interdomain interactions are highly conserved among close members of protein family DUF1355 and buried solvent accessible area for the hexamer is significant, the hexamer is most likely conserved as well. A light scattering experiment confirmed the presence of hexamer in solution.
-
===Cytoplasmic Protein STM3548 from Salmonella typhimurium===
+
Novel hexamerization motif is discovered in a conserved cytoplasmic protein from Salmonella typhimurium.,Petrova T, Cuff ME, Wu R, Kim Y, Holzle D, Joachimiak A J Struct Funct Genomics. 2007 Mar;8(1):19-25. Epub 2007 Oct 30. PMID:17968677<ref>PMID:17968677</ref>
-
 
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
==About this Structure==
+
</div>
-
2GK3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium_lt2 Salmonella typhimurium lt2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GK3 OCA].
+
<div class="pdbe-citations 2gk3" style="background-color:#fffaf0;"></div>
-
[[Category: Salmonella typhimurium lt2]]
+
== References ==
-
[[Category: Single protein]]
+
<references/>
-
[[Category: Cuff, M E.]]
+
__TOC__
-
[[Category: Holzle, D.]]
+
</StructureSection>
-
[[Category: Joachimiak, A.]]
+
[[Category: Large Structures]]
-
[[Category: MCSG, Midwest Center for Structural Genomics.]]
+
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
-
[[Category: Petrova, T.]]
+
[[Category: Cuff ME]]
-
[[Category: Wu, R Y.]]
+
[[Category: Holzle D]]
-
[[Category: Mcsg]]
+
[[Category: Joachimiak A]]
-
[[Category: Midwest center for structural genomic]]
+
[[Category: Petrova T]]
-
[[Category: Protein structure initiative]]
+
[[Category: Wu RY]]
-
[[Category: Psi]]
+
-
[[Category: Salmonella typhimurium]]
+
-
[[Category: Stm3548]]
+
-
[[Category: Structural genomic]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 29 02:47:15 2008''
+

Current revision

Cytoplasmic Protein STM3548 from Salmonella typhimurium

PDB ID 2gk3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2gk3"
Personal tools