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1wxv

From Proteopedia

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{{Seed}}
 
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[[Image:1wxv.png|left|200px]]
 
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<!--
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==Solution structure of the ubiquitin domain of BCL-2 binding athanogene-1==
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The line below this paragraph, containing "STRUCTURE_1wxv", creates the "Structure Box" on the page.
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<StructureSection load='1wxv' size='340' side='right'caption='[[1wxv]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1wxv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WXV FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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-->
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wxv OCA], [https://pdbe.org/1wxv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wxv RCSB], [https://www.ebi.ac.uk/pdbsum/1wxv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wxv ProSAT], [https://www.topsan.org/Proteins/RSGI/1wxv TOPSAN]</span></td></tr>
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{{STRUCTURE_1wxv| PDB=1wxv | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BAG1_HUMAN BAG1_HUMAN] Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Inhibits the pro-apoptotic function of PPP1R15A, and has anti-apoptotic activity. Markedly increases the anti-cell death function of BCL2 induced by various stimuli.<ref>PMID:9305631</ref> <ref>PMID:9873016</ref> <ref>PMID:12724406</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wx/1wxv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wxv ConSurf].
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<div style="clear:both"></div>
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===Solution structure of the ubiquitin domain of BCL-2 binding athanogene-1===
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==See Also==
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*[[BAG family proteins 3D structures|BAG family proteins 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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1WXV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXV OCA].
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Inoue, M.]]
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[[Category: Inoue M]]
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[[Category: Kigawa, T.]]
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[[Category: Kigawa T]]
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[[Category: Muto, Y.]]
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[[Category: Muto Y]]
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[[Category: Niraula, T N.]]
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[[Category: Niraula TN]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S.]]
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[[Category: Apoptosis]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 29 05:36:15 2008''
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Current revision

Solution structure of the ubiquitin domain of BCL-2 binding athanogene-1

PDB ID 1wxv

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