1spv

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(New page: 200px<br /><applet load="1spv" size="450" color="white" frame="true" align="right" spinBox="true" caption="1spv, resolution 2.0&Aring;" /> '''Crystal Structure of ...)
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[[Image:1spv.gif|left|200px]]<br /><applet load="1spv" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1spv, resolution 2.0&Aring;" />
 
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'''Crystal Structure of the Putative Phosphatase of Escherichia coli, Northeast Structural Genomoics Target ER58'''<br />
 
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==About this Structure==
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==Crystal Structure of the Putative Phosphatase of Escherichia coli, Northeast Structural Genomoics Target ER58==
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1SPV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with MES as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1SPV OCA].
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<StructureSection load='1spv' size='340' side='right'caption='[[1spv]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1spv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SPV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SPV FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1spv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1spv OCA], [https://pdbe.org/1spv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1spv RCSB], [https://www.ebi.ac.uk/pdbsum/1spv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1spv ProSAT], [https://www.topsan.org/Proteins/NESGC/1spv TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/YMDB_ECOLI YMDB_ECOLI] Deacetylates O-acetyl-ADP ribose. Down-regulates ribonuclease 3 (RNase III) activity. Acts by interacting directly with the region of the ribonuclease that is required for dimerization/activation.<ref>PMID:19141481</ref> <ref>PMID:21257746</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sp/1spv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1spv ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Acton, T.B.]]
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[[Category: Acton TB]]
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[[Category: Forouhar, F.]]
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[[Category: Forouhar F]]
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[[Category: Hunt, J.F.]]
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[[Category: Hunt JF]]
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[[Category: Lee, I.]]
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[[Category: Lee I]]
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[[Category: Montelione, G.T.]]
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[[Category: Montelione GT]]
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[[Category: NESG, Northeast.Structural.Genomics.Consortium.]]
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[[Category: Tong L]]
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[[Category: Tong, L.]]
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[[Category: Vorobiev SM]]
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[[Category: Vorobiev, S.M.]]
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[[Category: Xiao R]]
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[[Category: Xiao, R.]]
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[[Category: MES]]
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[[Category: alpha/beta monomeric protein]]
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[[Category: nesg]]
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[[Category: northeast structural genomics consortium]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomics]]
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[[Category: structural genomoics]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 02:33:16 2007''
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Current revision

Crystal Structure of the Putative Phosphatase of Escherichia coli, Northeast Structural Genomoics Target ER58

PDB ID 1spv

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