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1sxs

From Proteopedia

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(New page: 200px<br /><applet load="1sxs" size="450" color="white" frame="true" align="right" spinBox="true" caption="1sxs, resolution 2.0&Aring;" /> '''Reduced bovine supero...)
Current revision (06:21, 23 August 2023) (edit) (undo)
 
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[[Image:1sxs.gif|left|200px]]<br /><applet load="1sxs" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1sxs, resolution 2.0&Aring;" />
 
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'''Reduced bovine superoxide dismutase at pH 5.0 complexed with thiocyanate'''<br />
 
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==About this Structure==
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==Reduced bovine superoxide dismutase at pH 5.0 complexed with thiocyanate==
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1SXS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with SCN, CU, ZN and CA as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1SXS OCA].
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<StructureSection load='1sxs' size='340' side='right'caption='[[1sxs]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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[[Category: Bos taurus]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[1sxs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SXS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SXS FirstGlance]. <br>
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[[Category: Superoxide dismutase]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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[[Category: Bruni, B.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Ferraroni, M.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sxs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sxs OCA], [https://pdbe.org/1sxs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sxs RCSB], [https://www.ebi.ac.uk/pdbsum/1sxs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sxs ProSAT]</span></td></tr>
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[[Category: Mangani, S.]]
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</table>
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[[Category: Orioli, P.]]
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== Function ==
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[[Category: Rypniewski, W.R.]]
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[https://www.uniprot.org/uniprot/SODC_BOVIN SODC_BOVIN] Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
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[[Category: CA]]
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== Evolutionary Conservation ==
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[[Category: CU]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: SCN]]
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Check<jmol>
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[[Category: ZN]]
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<jmolCheckbox>
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[[Category: oxidoreductase]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sx/1sxs_consurf.spt"</scriptWhenChecked>
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[[Category: superoxide acceptor]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sxs ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 02:49:39 2007''
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==See Also==
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*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Bos taurus]]
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[[Category: Large Structures]]
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[[Category: Bruni B]]
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[[Category: Ferraroni M]]
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[[Category: Mangani S]]
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[[Category: Orioli P]]
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[[Category: Rypniewski WR]]

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Reduced bovine superoxide dismutase at pH 5.0 complexed with thiocyanate

PDB ID 1sxs

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