2ri4

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{{Seed}}
 
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[[Image:2ri4.jpg|left|200px]]
 
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==Crystal Structure determination of Goat Methemoglobin at 2.7 Angstrom==
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The line below this paragraph, containing "STRUCTURE_2ri4", creates the "Structure Box" on the page.
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<StructureSection load='2ri4' size='340' side='right'caption='[[2ri4]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2ri4]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Capra_hircus Capra hircus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RI4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RI4 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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{{STRUCTURE_2ri4| PDB=2ri4 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ri4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ri4 OCA], [https://pdbe.org/2ri4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ri4 RCSB], [https://www.ebi.ac.uk/pdbsum/2ri4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ri4 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HBA1_CAPHI HBA1_CAPHI] Involved in oxygen transport from the lung to the various peripheral tissues. Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1. Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.[UniProtKB:P01946]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ri/2ri4_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ri4 ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure determination of Goat Methemoglobin at 2.7 Angstrom===
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==See Also==
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*[[Hemoglobin 3D structures|Hemoglobin 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_17909297}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 17909297 is the PubMed ID number.
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{{ABSTRACT_PUBMED_17909297}}
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==About this Structure==
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2RI4 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Capra_hircus Capra hircus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RI4 OCA].
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==Reference==
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Crystallization of sheep (Ovis aries) and goat (Capra hircus) haemoglobins under unbuffered low-salt conditions., Neelagandan K, Moorthy PS, Balasubramanian M, Ponnuswamy MN, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Oct 1;63(Pt, 10):887-9. Epub 2007 Sep 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17909297 17909297]
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[[Category: Capra hircus]]
[[Category: Capra hircus]]
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[[Category: Protein complex]]
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[[Category: Large Structures]]
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[[Category: Balasubramanian, M.]]
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[[Category: Balasubramanian M]]
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[[Category: Moorthy, P S.]]
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[[Category: Neelagandan K]]
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[[Category: Neelagandan, K.]]
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[[Category: Ponnuswamy MN]]
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[[Category: Ponnuswamy, M N.]]
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[[Category: Sathya Moorthy P]]
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[[Category: Allosteric mechanism]]
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[[Category: Heme]]
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[[Category: Iron]]
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[[Category: Low oxygen affinity]]
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[[Category: Metal-binding]]
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[[Category: Methemoglobin]]
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[[Category: Oxygen storage]]
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[[Category: Oxygen transport]]
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[[Category: Polymorphism]]
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[[Category: Transport]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 15 14:10:40 2008''
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Current revision

Crystal Structure determination of Goat Methemoglobin at 2.7 Angstrom

PDB ID 2ri4

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