3e4p

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{{Seed}}
 
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[[Image:3e4p.jpg|left|200px]]
 
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==Crystal structure of malonate occupied DctB==
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The line below this paragraph, containing "STRUCTURE_3e4p", creates the "Structure Box" on the page.
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<StructureSection load='3e4p' size='340' side='right'caption='[[3e4p]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3e4p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sinorhizobium_meliloti Sinorhizobium meliloti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E4P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E4P FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene>, <scene name='pdbligand=SR:STRONTIUM+ION'>SR</scene></td></tr>
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{{STRUCTURE_3e4p| PDB=3e4p | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e4p OCA], [https://pdbe.org/3e4p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e4p RCSB], [https://www.ebi.ac.uk/pdbsum/3e4p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e4p ProSAT]</span></td></tr>
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</table>
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===Crystal structure of malonate occupied DctB===
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== Function ==
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[https://www.uniprot.org/uniprot/DCTB_RHIME DCTB_RHIME] Member of the two-component regulatory system DctB/DctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates DctD in response to environmental signals.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 18725229 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e4/3e4p_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_18725229}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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3E4P is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sinorhizobium_meliloti Sinorhizobium meliloti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E4P OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3e4p ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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C4-dicarboxylates sensing mechanism revealed by the crystal structures of DctB sensor domain., Zhou YF, Nan B, Nan J, Ma Q, Panjikar S, Liang YH, Wang Y, Su XD, J Mol Biol. 2008 Oct 31;383(1):49-61. Epub 2008 Aug 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18725229 18725229]
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</StructureSection>
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[[Category: Histidine kinase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Sinorhizobium meliloti]]
[[Category: Sinorhizobium meliloti]]
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[[Category: Liang, Y H.]]
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[[Category: Liang YH]]
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[[Category: Nan, B Y.]]
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[[Category: Nan BY]]
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[[Category: Nan, J.]]
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[[Category: Nan J]]
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[[Category: Panjikar, S.]]
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[[Category: Panjikar S]]
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[[Category: Su, X D.]]
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[[Category: Su XD]]
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[[Category: Zhou, Y F.]]
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[[Category: Zhou YF]]
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[[Category: N-term helical dimerization domain]]
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[[Category: Pas domain]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 22 10:50:26 2008''
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Current revision

Crystal structure of malonate occupied DctB

PDB ID 3e4p

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