2ivg

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{{Seed}}
 
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[[Image:2ivg.jpg|left|200px]]
 
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==SITE DIRECTED MUTAGENESIS OF KEY RESIDUES INVOLVED IN THE CATALYTIC MECHANISM OF CYANASE==
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The line below this paragraph, containing "STRUCTURE_2ivg", creates the "Structure Box" on the page.
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<StructureSection load='2ivg' size='340' side='right'caption='[[2ivg]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2ivg]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IVG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IVG FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.87&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_2ivg| PDB=2ivg | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ivg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ivg OCA], [https://pdbe.org/2ivg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ivg RCSB], [https://www.ebi.ac.uk/pdbsum/2ivg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ivg ProSAT]</span></td></tr>
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</table>
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===SITE DIRECTED MUTAGENESIS OF KEY RESIDUES INVOLVED IN THE CATALYTIC MECHANISM OF CYANASE===
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== Function ==
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[https://www.uniprot.org/uniprot/CYNS_ECOLI CYNS_ECOLI] Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_10801492}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 10801492 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iv/2ivg_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_10801492}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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2IVG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IVG OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ivg ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Structure of cyanase reveals that a novel dimeric and decameric arrangement of subunits is required for formation of the enzyme active site., Walsh MA, Otwinowski Z, Perrakis A, Anderson PM, Joachimiak A, Structure. 2000 May 15;8(5):505-14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10801492 10801492]
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</StructureSection>
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[[Category: Cyanase]]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Anderson, P M.]]
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[[Category: Anderson PM]]
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[[Category: Guilloton, M.]]
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[[Category: Guilloton M]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak A]]
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[[Category: Walsh, M A.]]
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[[Category: Walsh MA]]
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[[Category: Cyanate degradation]]
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[[Category: Lyase]]
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[[Category: Mcsg]]
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[[Category: Midwest center for structural genomic]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 29 10:42:18 2008''
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Current revision

SITE DIRECTED MUTAGENESIS OF KEY RESIDUES INVOLVED IN THE CATALYTIC MECHANISM OF CYANASE

PDB ID 2ivg

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