2i7p

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:02, 21 February 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2i7p.png|left|200px]]
 
-
<!--
+
==Crystal structure of human PANK3 in complex with AcCoA==
-
The line below this paragraph, containing "STRUCTURE_2i7p", creates the "Structure Box" on the page.
+
<StructureSection load='2i7p' size='340' side='right'caption='[[2i7p]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2i7p]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I7P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I7P FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene></td></tr>
-
{{STRUCTURE_2i7p| PDB=2i7p | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i7p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i7p OCA], [https://pdbe.org/2i7p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i7p RCSB], [https://www.ebi.ac.uk/pdbsum/2i7p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i7p ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/PANK3_HUMAN PANK3_HUMAN] Plays a role in the physiological regulation of the intracellular CoA concentration (By similarity).
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i7/2i7p_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i7p ConSurf].
 +
<div style="clear:both"></div>
-
===Crystal structure of human PANK3 in complex with AcCoA===
+
==See Also==
-
 
+
*[[Pantothenate kinase 3D structures|Pantothenate kinase 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_17631502}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 17631502 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_17631502}}
+
-
 
+
-
==About this Structure==
+
-
2I7P is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I7P OCA].
+
-
 
+
-
==Reference==
+
-
Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder., Hong BS, Senisterra G, Rabeh WM, Vedadi M, Leonardi R, Zhang YM, Rock CO, Jackowski S, Park HW, J Biol Chem. 2007 Sep 21;282(38):27984-93. Epub 2007 Jul 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17631502 17631502]
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Pantothenate kinase]]
+
[[Category: Large Structures]]
-
[[Category: Single protein]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Arrowsmith, C H.]]
+
[[Category: Bochkarev A]]
-
[[Category: Bochkarev, A.]]
+
[[Category: Edwards AM]]
-
[[Category: Edwards, A M.]]
+
[[Category: Finerty P]]
-
[[Category: Finerty, P.]]
+
[[Category: Hong BS]]
-
[[Category: Hong, B S.]]
+
[[Category: Loppnau P]]
-
[[Category: Loppnau, P.]]
+
[[Category: Park HW]]
-
[[Category: Park, H W.]]
+
[[Category: Shen L]]
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[[Category: Sundstrom M]]
-
[[Category: Shen, L.]]
+
[[Category: Tempel W]]
-
[[Category: Sundstrom, M.]]
+
[[Category: Wang L]]
-
[[Category: Tempel, W.]]
+
[[Category: Weigelt J]]
-
[[Category: Wang, L.]]
+
-
[[Category: Weigelt, J.]]
+
-
[[Category: Pank]]
+
-
[[Category: Sgc]]
+
-
[[Category: Structural genomic]]
+
-
[[Category: Structural genomics consortium]]
+
-
[[Category: Transferase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 5 10:47:38 2008''
+

Current revision

Crystal structure of human PANK3 in complex with AcCoA

PDB ID 2i7p

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2i7p"
Personal tools