1zyl

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{{Seed}}
 
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[[Image:1zyl.png|left|200px]]
 
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==Crystal Structure of Hypothetical Protein YihE from Escherichia coli==
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The line below this paragraph, containing "STRUCTURE_1zyl", creates the "Structure Box" on the page.
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<StructureSection load='1zyl' size='340' side='right'caption='[[1zyl]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1zyl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZYL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZYL FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zyl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zyl OCA], [https://pdbe.org/1zyl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zyl RCSB], [https://www.ebi.ac.uk/pdbsum/1zyl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zyl ProSAT], [https://www.topsan.org/Proteins/BSGI/1zyl TOPSAN]</span></td></tr>
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{{STRUCTURE_1zyl| PDB=1zyl | SCENE= }}
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</table>
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== Function ==
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===Crystal Structure of Hypothetical Protein YihE from Escherichia coli===
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[https://www.uniprot.org/uniprot/SRKA_ECOLI SRKA_ECOLI] A protein kinase that (auto)phosphorylates on Ser and Thr residues (PubMed:17302814). Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Protects cells from stress by antagonizing the MazE-MazF TA module, probably indirectly as it has not been seen to phosphorylate MazE, MazF or MazG (PubMed:23416055). Probably involved in the extracytoplasmic stress response (PubMed:9159398).[HAMAP-Rule:MF_01497]<ref>PMID:17302814</ref> <ref>PMID:23416055</ref> <ref>PMID:9159398</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_17302814}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 17302814 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zy/1zyl_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_17302814}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zyl ConSurf].
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1ZYL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZYL OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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Crystal structure of a novel prokaryotic Ser/Thr kinase and its implication in the Cpx stress response pathway., Zheng J, He C, Singh VK, Martin NL, Jia Z, Mol Microbiol. 2007 Mar;63(5):1360-71. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17302814 17302814]
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: BSGI, Montreal-Kingston Bacterial Structural Genomics Initiative.]]
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[[Category: Jia Z]]
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[[Category: Jia, Z.]]
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[[Category: Zheng J]]
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[[Category: Zheng, J.]]
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[[Category: Bsgi]]
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[[Category: Hypothetical protein]]
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[[Category: Montreal-kingston bacterial structural genomics initiative]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Putative protein kinase]]
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[[Category: Structural genomic]]
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[[Category: Unknown function]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 5 10:47:44 2008''
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Current revision

Crystal Structure of Hypothetical Protein YihE from Escherichia coli

PDB ID 1zyl

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