3ebq
From Proteopedia
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- | {{Seed}} | ||
- | [[Image:3ebq.jpg|left|200px]] | ||
- | + | ==Crystal structure of human PPPDE1== | |
- | + | <StructureSection load='3ebq' size='340' side='right'caption='[[3ebq]], [[Resolution|resolution]] 1.90Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[3ebq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EBQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EBQ FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ebq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ebq OCA], [https://pdbe.org/3ebq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ebq RCSB], [https://www.ebi.ac.uk/pdbsum/3ebq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ebq ProSAT]</span></td></tr> | |
- | + | </table> | |
- | + | == Function == | |
- | + | [https://www.uniprot.org/uniprot/DESI1_HUMAN DESI1_HUMAN] Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins. Has isopeptidase but not SUMO-processing activity. Desumoylates ZBTB46 (By similarity). | |
- | + | == Evolutionary Conservation == | |
- | == | + | [[Image:Consurf_key_small.gif|200px|right]] |
- | + | Check<jmol> | |
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eb/3ebq_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ebq ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: Akutsu | + | [[Category: Akutsu M]] |
- | [[Category: Arrowsmith | + | [[Category: Arrowsmith CH]] |
- | [[Category: Botchkarev | + | [[Category: Botchkarev A]] |
- | [[Category: Bountra | + | [[Category: Bountra C]] |
- | [[Category: Dhe-Paganon | + | [[Category: Dhe-Paganon S]] |
- | [[Category: Edwards | + | [[Category: Edwards AM]] |
- | [[Category: Li | + | [[Category: Li Y]] |
- | [[Category: Qiu | + | [[Category: Qiu L]] |
- | + | [[Category: Slessarev Y]] | |
- | [[Category: Slessarev | + | [[Category: Walker JR]] |
- | [[Category: Walker | + | [[Category: Weigelt J]] |
- | [[Category: Weigelt | + | |
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Current revision
Crystal structure of human PPPDE1
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Categories: Homo sapiens | Large Structures | Akutsu M | Arrowsmith CH | Botchkarev A | Bountra C | Dhe-Paganon S | Edwards AM | Li Y | Qiu L | Slessarev Y | Walker JR | Weigelt J