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1n7k

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{{Seed}}
 
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[[Image:1n7k.png|left|200px]]
 
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==Unique tetrameric structure of deoxyribose phosphate aldolase from Aeropyrum pernix==
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The line below this paragraph, containing "STRUCTURE_1n7k", creates the "Structure Box" on the page.
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<StructureSection load='1n7k' size='340' side='right'caption='[[1n7k]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1n7k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N7K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N7K FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n7k OCA], [https://pdbe.org/1n7k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n7k RCSB], [https://www.ebi.ac.uk/pdbsum/1n7k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n7k ProSAT], [https://www.topsan.org/Proteins/RSGI/1n7k TOPSAN]</span></td></tr>
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{{STRUCTURE_1n7k| PDB=1n7k | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DEOC_AERPE DEOC_AERPE] Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.<ref>PMID:12529358</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n7/1n7k_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n7k ConSurf].
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<div style="clear:both"></div>
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===Unique tetrameric structure of deoxyribose phosphate aldolase from Aeropyrum pernix===
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==See Also==
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*[[Aldolase 3D structures|Aldolase 3D structures]]
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== References ==
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<!--
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_12529358}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 12529358 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_12529358}}
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==About this Structure==
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1N7K is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N7K OCA].
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==Reference==
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The first crystal structure of archaeal aldolase. Unique tetrameric structure of 2-deoxy-d-ribose-5-phosphate aldolase from the hyperthermophilic archaea Aeropyrum pernix., Sakuraba H, Tsuge H, Shimoya I, Kawakami R, Goda S, Kawarabayasi Y, Katunuma N, Ago H, Miyano M, Ohshima T, J Biol Chem. 2003 Mar 21;278(12):10799-806. Epub 2003 Jan 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12529358 12529358]
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[[Category: Aeropyrum pernix]]
[[Category: Aeropyrum pernix]]
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[[Category: Deoxyribose-phosphate aldolase]]
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[[Category: Large Structures]]
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[[Category: Ago, H.]]
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[[Category: Ago H]]
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[[Category: Katunuma, N.]]
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[[Category: Katunuma N]]
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[[Category: Miyano, M.]]
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[[Category: Miyano M]]
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[[Category: Ohshima, T.]]
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[[Category: Ohshima T]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Sakuraba H]]
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[[Category: Sakuraba, H.]]
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[[Category: Shimoya I]]
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[[Category: Shimoya, I.]]
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[[Category: Tsuge H]]
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[[Category: Tsuge, H.]]
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[[Category: A pernix]]
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[[Category: Aldolase]]
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[[Category: Alpha-beta tim barrel]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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[[Category: Tetramer]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 09:59:12 2008''
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Current revision

Unique tetrameric structure of deoxyribose phosphate aldolase from Aeropyrum pernix

PDB ID 1n7k

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