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2fmu

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{{Seed}}
 
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[[Image:2fmu.png|left|200px]]
 
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==Crystal structure of a tat-interacting protein homologue (htatip2, aw111545, cc3, tip30) from mus musculus at 2.30 A resolution==
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The line below this paragraph, containing "STRUCTURE_2fmu", creates the "Structure Box" on the page.
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<StructureSection load='2fmu' size='340' side='right'caption='[[2fmu]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2fmu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FMU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FMU FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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{{STRUCTURE_2fmu| PDB=2fmu | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fmu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fmu OCA], [https://pdbe.org/2fmu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fmu RCSB], [https://www.ebi.ac.uk/pdbsum/2fmu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fmu ProSAT], [https://www.topsan.org/Proteins/JCSG/2fmu TOPSAN]</span></td></tr>
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</table>
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===Crystal structure of Tat-interacting protein 30 kDa (HIV-1 tat interactive protein 2, 30 kDa homolog) (Human) (16924205) from Mus musculus at 2.30 A resolution===
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== Function ==
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[https://www.uniprot.org/uniprot/HTAI2_MOUSE HTAI2_MOUSE] Oxidoreductase required for tumor suppression. NADPH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import.<ref>PMID:14695192</ref>
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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2FMU is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FMU OCA].
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fm/2fmu_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fmu ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: JCSG, Joint Center for Structural Genomics.]]
 
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[[Category: 16924205]]
 
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[[Category: Jcsg]]
 
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[[Category: Joint center for structural genomic]]
 
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[[Category: Protein structure initiative]]
 
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[[Category: Psi]]
 
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[[Category: Structural genomic]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 10:02:55 2008''
 

Current revision

Crystal structure of a tat-interacting protein homologue (htatip2, aw111545, cc3, tip30) from mus musculus at 2.30 A resolution

PDB ID 2fmu

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