2k50

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:44, 1 May 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2k50.png|left|200px]]
 
-
<!--
+
==Solution NMR Structure of the replication Factor A Related Protein from Methanobacterium thermoautotrophicum. Northeast Structural Genomics Target TR91A.==
-
The line below this paragraph, containing "STRUCTURE_2k50", creates the "Structure Box" on the page.
+
<StructureSection load='2k50' size='340' side='right'caption='[[2k50]]' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2k50]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus_str._Delta_H Methanothermobacter thermautotrophicus str. Delta H]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K50 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K50 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k50 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k50 OCA], [https://pdbe.org/2k50 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k50 RCSB], [https://www.ebi.ac.uk/pdbsum/2k50 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k50 ProSAT], [https://www.topsan.org/Proteins/NESGC/2k50 TOPSAN]</span></td></tr>
-
{{STRUCTURE_2k50| PDB=2k50 | SCENE= }}
+
</table>
-
 
+
== Function ==
-
===Solution NMR Structure of the replication Factor A Related Protein from Methanobacterium thermoautotrophicum. Northeast Structural Genomics Target TR91A.===
+
[https://www.uniprot.org/uniprot/RPA_METTH RPA_METTH] Inhibits DNA polymerase activity of PolB, which can be overcome by RFC and PNCA. Stimulates 3'-to 5'-exonuclease activity of PolB at 30 degrees Celsius, but has no effect at 50 or 70 degrees Celsius. Bind ssDNA and replication forks; replication forks structures bind both Hel308 and this protein. Has no effect on helicase activity of Hel308; may help target the helicase to DNA substrates that require DNA re-modeling.<ref>PMID:10497247</ref> <ref>PMID:21195035</ref>
-
 
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
==About this Structure==
+
Check<jmol>
-
2K50 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus_str._delta_h Methanothermobacter thermautotrophicus str. delta h]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K50 OCA].
+
<jmolCheckbox>
-
[[Category: Methanothermobacter thermautotrophicus str. delta h]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k5/2k50_consurf.spt"</scriptWhenChecked>
-
[[Category: Acton, T B.]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: Ciccosanti, C.]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: Everett, J K.]]
+
</jmolCheckbox>
-
[[Category: Foote, E L.]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k50 ConSurf].
-
[[Category: Jiang, M.]]
+
<div style="clear:both"></div>
-
[[Category: Maglaqui, M.]]
+
== References ==
-
[[Category: Montelione, G T.]]
+
<references/>
-
[[Category: NESG, Northeast Structural Genomics Consortium.]]
+
__TOC__
-
[[Category: Nair, R.]]
+
</StructureSection>
-
[[Category: Rossi, P.]]
+
[[Category: Large Structures]]
-
[[Category: Rost, B.]]
+
[[Category: Methanothermobacter thermautotrophicus str. Delta H]]
-
[[Category: Swapna, G.]]
+
[[Category: Acton TB]]
-
[[Category: Xiao, R.]]
+
[[Category: Ciccosanti C]]
-
[[Category: Nesg]]
+
[[Category: Everett JK]]
-
[[Category: Northeast structural genomics consortium]]
+
[[Category: Foote EL]]
-
[[Category: Protein structure initiative]]
+
[[Category: Jiang M]]
-
[[Category: Psi-2]]
+
[[Category: Maglaqui M]]
-
[[Category: Structural genomic]]
+
[[Category: Montelione GT]]
-
[[Category: Uncharacterized protein]]
+
[[Category: Nair R]]
-
[[Category: Unknown function]]
+
[[Category: Rossi P]]
-
 
+
[[Category: Rost B]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 10:12:07 2008''
+
[[Category: Swapna G]]
 +
[[Category: Xiao R]]

Current revision

Solution NMR Structure of the replication Factor A Related Protein from Methanobacterium thermoautotrophicum. Northeast Structural Genomics Target TR91A.

PDB ID 2k50

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2k50"
Personal tools