1v89
From Proteopedia
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- | {{Seed}} | ||
- | [[Image:1v89.png|left|200px]] | ||
- | + | ==Solution Structure of the Pleckstrin Homology Domain of Human KIAA0053 Protein== | |
- | + | <StructureSection load='1v89' size='340' side='right'caption='[[1v89]]' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[1v89]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V89 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V89 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v89 OCA], [https://pdbe.org/1v89 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v89 RCSB], [https://www.ebi.ac.uk/pdbsum/1v89 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v89 ProSAT], [https://www.topsan.org/Proteins/RSGI/1v89 TOPSAN]</span></td></tr> | |
- | + | </table> | |
- | + | == Function == | |
- | + | [https://www.uniprot.org/uniprot/RHG25_HUMAN RHG25_HUMAN] GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By similarity). | |
- | + | == Evolutionary Conservation == | |
- | + | [[Image:Consurf_key_small.gif|200px|right]] | |
- | == | + | Check<jmol> |
- | + | <jmolCheckbox> | |
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v8/1v89_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v89 ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Hirota | + | [[Category: Large Structures]] |
- | [[Category: Inoue | + | [[Category: Hirota H]] |
- | [[Category: Kigawa | + | [[Category: Inoue M]] |
- | [[Category: Koshiba | + | [[Category: Kigawa T]] |
- | [[Category: Li | + | [[Category: Koshiba S]] |
- | + | [[Category: Li H]] | |
- | [[Category: Tochio | + | [[Category: Tochio N]] |
- | [[Category: Yokoyama | + | [[Category: Yokoyama S]] |
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Current revision
Solution Structure of the Pleckstrin Homology Domain of Human KIAA0053 Protein
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Categories: Homo sapiens | Large Structures | Hirota H | Inoue M | Kigawa T | Koshiba S | Li H | Tochio N | Yokoyama S