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2z0o
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:2z0o.png|left|200px]] | ||
| - | + | ==Crystal structure of APPL1-BAR-PH domain== | |
| - | + | <StructureSection load='2z0o' size='340' side='right'caption='[[2z0o]], [[Resolution|resolution]] 2.58Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2z0o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z0O OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2Z0O FirstGlance]. <br> | |
| - | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2z0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z0o OCA], [http://pdbe.org/2z0o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2z0o RCSB], [http://www.ebi.ac.uk/pdbsum/2z0o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2z0o ProSAT], [http://www.topsan.org/Proteins/RSGI/2z0o TOPSAN]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [[http://www.uniprot.org/uniprot/DP13A_HUMAN DP13A_HUMAN]] Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction.<ref>PMID:10490823</ref> <ref>PMID:15016378</ref> | |
| - | + | == Evolutionary Conservation == | |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | == | + | Check<jmol> |
| - | + | <jmolCheckbox> | |
| - | [[Category: | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z0/2z0o_consurf.spt"</scriptWhenChecked> |
| - | [[Category: Kato-Murayama, M | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [[Category: Murayama, K | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | [[Category: | + | </jmolCheckbox> |
| - | [[Category: Shirouzu, M | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z0o ConSurf]. |
| - | [[Category: Terada, T | + | <div style="clear:both"></div> |
| - | [[Category: Yokoyama, S | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Kato-Murayama, M]] | ||
| + | [[Category: Murayama, K]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Shirouzu, M]] | ||
| + | [[Category: Terada, T]] | ||
| + | [[Category: Yokoyama, S]] | ||
[[Category: Cell cycle]] | [[Category: Cell cycle]] | ||
[[Category: Coiled coil]] | [[Category: Coiled coil]] | ||
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[[Category: Nucleus]] | [[Category: Nucleus]] | ||
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
| - | [[Category: Riken structural genomics/proteomics initiative]] | ||
[[Category: Rsgi]] | [[Category: Rsgi]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
| - | [[Category: Structural genomic]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 11:30:24 2008'' | ||
Current revision
Crystal structure of APPL1-BAR-PH domain
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Categories: Human | Large Structures | Kato-Murayama, M | Murayama, K | Structural genomic | Shirouzu, M | Terada, T | Yokoyama, S | Cell cycle | Coiled coil | Endosome | Helix bundle | Membrane | National project on protein structural and functional analyse | Nppsfa | Nucleus | Phosphorylation | Rsgi | Signaling protein
