1o0x

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{{Seed}}
 
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[[Image:1o0x.png|left|200px]]
 
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==Crystal structure of Methionine aminopeptidase (TM1478) from Thermotoga maritima at 1.90 A resolution==
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The line below this paragraph, containing "STRUCTURE_1o0x", creates the "Structure Box" on the page.
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<StructureSection load='1o0x' size='340' side='right'caption='[[1o0x]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1o0x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O0X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1O0X FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1o0x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o0x OCA], [https://pdbe.org/1o0x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1o0x RCSB], [https://www.ebi.ac.uk/pdbsum/1o0x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1o0x ProSAT], [https://www.topsan.org/Proteins/JCSG/1o0x TOPSAN]</span></td></tr>
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{{STRUCTURE_1o0x| PDB=1o0x | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9X1I7_THEMA Q9X1I7_THEMA] Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.[HAMAP-Rule:MF_01974]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o0/1o0x_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1o0x ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of Methionine aminopeptidase (TM1478) from Thermotoga maritima at 1.90 A resolution===
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==See Also==
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*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1O0X is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O0X OCA].
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[[Category: Large Structures]]
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==Reference==
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Crystal structure of a methionine aminopeptidase (TM1478) from Thermotoga maritima at 1.9 A resolution., Spraggon G, Schwarzenbacher R, Kreusch A, McMullan D, Brinen LS, Canaves JM, Dai X, Deacon AM, Elsliger MA, Eshagi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Jaroszewski L, Karlak C, Klock HE, Koesema E, Kovarik JS, Kuhn P, McPhillips TM, Miller MD, Morse A, Moy K, Ouyang J, Page R, Quijano K, Rezezadeh F, Robb A, Sims E, Stevens RC, van den Bedem H, Velasquez J, Vincent J, von Delft F, Wang X, West B, Wolf G, Xu Q, Hodgson KO, Wooley J, Lesley SA, Wilson IA, Proteins. 2004 Aug 1;56(2):396-400. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15211524 15211524]
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[[Category: Methionyl aminopeptidase]]
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[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: JCSG, Joint Center for Structural Genomics.]]
 
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[[Category: Jcsg]]
 
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[[Category: Joint center for structural genomic]]
 
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[[Category: Methionine aminopeptidase]]
 
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[[Category: Protein structure initiative]]
 
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[[Category: Psi]]
 
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[[Category: Structural genomic]]
 
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[[Category: Tm1478]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 12:02:55 2008''
 

Current revision

Crystal structure of Methionine aminopeptidase (TM1478) from Thermotoga maritima at 1.90 A resolution

PDB ID 1o0x

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