1wj9

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{{Seed}}
 
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[[Image:1wj9.png|left|200px]]
 
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==Crystal structure of a CRISPR-associated protein from thermus thermophilus==
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The line below this paragraph, containing "STRUCTURE_1wj9", creates the "Structure Box" on the page.
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<StructureSection load='1wj9' size='340' side='right'caption='[[1wj9]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1wj9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WJ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WJ9 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wj9 OCA], [https://pdbe.org/1wj9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wj9 RCSB], [https://www.ebi.ac.uk/pdbsum/1wj9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wj9 ProSAT], [https://www.topsan.org/Proteins/RSGI/1wj9 TOPSAN]</span></td></tr>
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{{STRUCTURE_1wj9| PDB=1wj9 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CAS6_THET8 CAS6_THET8] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). This enzyme processes pre-crRNA into individual crRNA units, but may not actually undergo enzyme turnover, retaining the crRNA product (PubMed:21572442). Generates a 2',3'-cyclic phosphodiester.<ref>PMID:21572442</ref> <ref>PMID:21572444</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wj/1wj9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wj9 ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of a CRISPR-associated protein from thermus thermophilus===
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==See Also==
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*[[CRISPR type I-E (Cascade)|CRISPR type I-E (Cascade)]]
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*[[CRISPR-Cas|CRISPR-Cas]]
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*[[Endonuclease 3D structures|Endonuclease 3D structures]]
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The line below this paragraph, {{ABSTRACT_PUBMED_16672237}}, adds the Publication Abstract to the page
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== References ==
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(as it appears on PubMed at http://www.pubmed.gov), where 16672237 is the PubMed ID number.
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<references/>
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__TOC__
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{{ABSTRACT_PUBMED_16672237}}
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</StructureSection>
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[[Category: Large Structures]]
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==About this Structure==
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1WJ9 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WJ9 OCA].
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==Reference==
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Crystal structure of hypothetical protein TTHB192 from Thermus thermophilus HB8 reveals a new protein family with an RNA recognition motif-like domain., Ebihara A, Yao M, Masui R, Tanaka I, Yokoyama S, Kuramitsu S, Protein Sci. 2006 Jun;15(6):1494-9. Epub 2006 May 2. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16672237 16672237]
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[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
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[[Category: Ebihara, A.]]
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[[Category: Ebihara A]]
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[[Category: Kuramitsu, S.]]
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[[Category: Kuramitsu S]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Yao M]]
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[[Category: Yao, M.]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S.]]
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[[Category: Alpha and beta protein]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 12:43:59 2008''
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Current revision

Crystal structure of a CRISPR-associated protein from thermus thermophilus

PDB ID 1wj9

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