2cpd

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:28, 22 May 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2cpd.png|left|200px]]
 
-
<!--
+
==Solution structure of the RNA recognition motif of human APOBEC-1 complementation factor, ACF==
-
The line below this paragraph, containing "STRUCTURE_2cpd", creates the "Structure Box" on the page.
+
<StructureSection load='2cpd' size='340' side='right'caption='[[2cpd]]' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2cpd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CPD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CPD FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cpd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cpd OCA], [https://pdbe.org/2cpd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cpd RCSB], [https://www.ebi.ac.uk/pdbsum/2cpd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cpd ProSAT], [https://www.topsan.org/Proteins/RSGI/2cpd TOPSAN]</span></td></tr>
-
{{STRUCTURE_2cpd| PDB=2cpd | SCENE= }}
+
</table>
-
 
+
== Function ==
-
===Solution structure of the RNA recognition motif of human APOBEC-1 complementation factor, ACF===
+
[https://www.uniprot.org/uniprot/A1CF_HUMAN A1CF_HUMAN] Essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA. Binds to APOB mRNA and is probably responsible for docking the catalytic subunit, APOBEC1, to the mRNA to allow it to deaminate its target cytosine. The complex also protects the edited APOB mRNA from nonsense-mediated decay.<ref>PMID:10781591</ref> <ref>PMID:10669759</ref> <ref>PMID:12881431</ref>
-
 
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
==About this Structure==
+
Check<jmol>
-
2CPD is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CPD OCA].
+
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cp/2cpd_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cpd ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Inoue, M.]]
+
[[Category: Large Structures]]
-
[[Category: Kigawa, T.]]
+
[[Category: Inoue M]]
-
[[Category: Muto, Y.]]
+
[[Category: Kigawa T]]
-
[[Category: Nagata, T.]]
+
[[Category: Muto Y]]
-
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+
[[Category: Nagata T]]
-
[[Category: Shirouzu, M.]]
+
[[Category: Shirouzu M]]
-
[[Category: Terada, T.]]
+
[[Category: Terada T]]
-
[[Category: Yokoyama, S.]]
+
[[Category: Yokoyama S]]
-
[[Category: National project on protein structural and functional analyse]]
+
-
[[Category: Nppsfa]]
+
-
[[Category: Riken structural genomics/proteomics initiative]]
+
-
[[Category: Rna recognition motif]]
+
-
[[Category: Rnp]]
+
-
[[Category: Rrm]]
+
-
[[Category: Rsgi]]
+
-
[[Category: Structural genomic]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 13:42:19 2008''
+

Current revision

Solution structure of the RNA recognition motif of human APOBEC-1 complementation factor, ACF

PDB ID 2cpd

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2cpd"
Personal tools