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2dzv

From Proteopedia

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{{Seed}}
 
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[[Image:2dzv.png|left|200px]]
 
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<!--
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==Structure of mutant tryptophan synthase alpha-subunit (D146A) from a hyperthermophile, Pyrococcus furiosus==
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The line below this paragraph, containing "STRUCTURE_2dzv", creates the "Structure Box" on the page.
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<StructureSection load='2dzv' size='340' side='right'caption='[[2dzv]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2dzv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DZV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DZV FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dzv OCA], [https://pdbe.org/2dzv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dzv RCSB], [https://www.ebi.ac.uk/pdbsum/2dzv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dzv ProSAT], [https://www.topsan.org/Proteins/RSGI/2dzv TOPSAN]</span></td></tr>
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{{STRUCTURE_2dzv| PDB=2dzv | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRPA_PYRFU TRPA_PYRFU] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dz/2dzv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dzv ConSurf].
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<div style="clear:both"></div>
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===Structure of mutant tryptophan synthase alpha-subunit (D146A) from a hyperthermophile, Pyrococcus furiosus===
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==See Also==
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*[[Tryptophan synthase 3D structures|Tryptophan synthase 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_11118452}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 11118452 is the PubMed ID number.
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-->
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{{ABSTRACT_PUBMED_11118452}}
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==About this Structure==
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2DZV is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DZV OCA].
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==Reference==
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Entropic stabilization of the tryptophan synthase alpha-subunit from a hyperthermophile, Pyrococcus furiosus. X-ray analysis and calorimetry., Yamagata Y, Ogasahara K, Hioki Y, Lee SJ, Nakagawa A, Nakamura H, Ishida M, Kuramitsu S, Yutani K, J Biol Chem. 2001 Apr 6;276(14):11062-71. Epub 2000 Dec 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11118452 11118452]
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[[Category: Pyrococcus furiosus]]
[[Category: Pyrococcus furiosus]]
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[[Category: Tryptophan synthase]]
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[[Category: Ogasahara K]]
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[[Category: Ogasahara, K.]]
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[[Category: Yamagata Y]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Yutani K]]
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[[Category: Yamagata, Y.]]
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[[Category: Yutani, K.]]
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[[Category: Calorimetry]]
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[[Category: Hyperthermophile]]
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[[Category: Lyase]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Pyrococcus furiosus]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Stability]]
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[[Category: Structural genomic]]
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[[Category: Tryptophan synthase alpha-subunit]]
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[[Category: X-ray analysis]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 13:51:59 2008''
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Current revision

Structure of mutant tryptophan synthase alpha-subunit (D146A) from a hyperthermophile, Pyrococcus furiosus

PDB ID 2dzv

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