1su2

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:33, 14 February 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1su2.png|left|200px]]
 
-
<!--
+
==CRYSTAL STRUCTURE OF THE NUDIX HYDROLASE DR1025 IN COMPLEX WITH ATP==
-
The line below this paragraph, containing "STRUCTURE_1su2", creates the "Structure Box" on the page.
+
<StructureSection load='1su2' size='340' side='right'caption='[[1su2]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1su2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SU2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SU2 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
{{STRUCTURE_1su2| PDB=1su2 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1su2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1su2 OCA], [https://pdbe.org/1su2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1su2 RCSB], [https://www.ebi.ac.uk/pdbsum/1su2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1su2 ProSAT], [https://www.topsan.org/Proteins/BSGC/1su2 TOPSAN]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Y1025_DEIRA Y1025_DEIRA] Hydrolase that can act as a nucleoside triphosphatase and a dinucleoside polyphosphate pyrophosphatase. The best substrates are 8-oxo-dGTP and 8-oxo-GTP. Other substrates include Ap4A, dGTP and GTP. May be involved in protection from damage caused by radiation.<ref>PMID:23481913</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/su/1su2_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1su2 ConSurf].
 +
<div style="clear:both"></div>
-
===CRYSTAL STRUCTURE OF THE NUDIX HYDROLASE DR1025 IN COMPLEX WITH ATP===
+
==See Also==
-
 
+
*[[Nudix hydrolase|Nudix hydrolase]]
-
 
+
*[[Nudix hydrolase 3D structures|Nudix hydrolase 3D structures]]
-
<!--
+
*[[7%2C8-dihydro-8-oxoguanine triphosphatase 3D structures|7%2C8-dihydro-8-oxoguanine triphosphatase 3D structures]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_15123424}}, adds the Publication Abstract to the page
+
== References ==
-
(as it appears on PubMed at http://www.pubmed.gov), where 15123424 is the PubMed ID number.
+
<references/>
-
-->
+
__TOC__
-
{{ABSTRACT_PUBMED_15123424}}
+
</StructureSection>
-
 
+
-
==About this Structure==
+
-
1SU2 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SU2 OCA].
+
-
 
+
-
==Reference==
+
-
Structural studies of the Nudix hydrolase DR1025 from Deinococcus radiodurans and its ligand complexes., Ranatunga W, Hill EE, Mooster JL, Holbrook EL, Schulze-Gahmen U, Xu W, Bessman MJ, Brenner SE, Holbrook SR, J Mol Biol. 2004 May 21;339(1):103-16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15123424 15123424]
+
[[Category: Deinococcus radiodurans]]
[[Category: Deinococcus radiodurans]]
-
[[Category: BSGC, Berkeley Structural Genomics Center.]]
+
[[Category: Large Structures]]
-
[[Category: Bessman, M J.]]
+
[[Category: Bessman MJ]]
-
[[Category: Brenner, S E.]]
+
[[Category: Brenner SE]]
-
[[Category: Hill, E E.]]
+
[[Category: Hill EE]]
-
[[Category: Holbrook, E L.]]
+
[[Category: Holbrook EL]]
-
[[Category: Holbrook, S R.]]
+
[[Category: Holbrook SR]]
-
[[Category: Mooster, J L.]]
+
[[Category: Mooster JL]]
-
[[Category: Ranatunga, W.]]
+
[[Category: Ranatunga W]]
-
[[Category: Schulze-Gahmen, U.]]
+
[[Category: Schulze-Gahmen U]]
-
[[Category: Xu, W.]]
+
[[Category: Xu W]]
-
[[Category: Alpha-beta-alpha sandwich]]
+
-
[[Category: Berkeley structural genomics center]]
+
-
[[Category: Bsgc structure funded by nih]]
+
-
[[Category: Nudix fold]]
+
-
[[Category: Protein structure initiative]]
+
-
[[Category: Psi]]
+
-
[[Category: Structural genomic]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 13:52:17 2008''
+

Current revision

CRYSTAL STRUCTURE OF THE NUDIX HYDROLASE DR1025 IN COMPLEX WITH ATP

PDB ID 1su2

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1su2"
Personal tools