1g60

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{{Seed}}
 
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[[Image:1g60.png|left|200px]]
 
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==Crystal Structure of Methyltransferase MboIIa (Moraxella bovis)==
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The line below this paragraph, containing "STRUCTURE_1g60", creates the "Structure Box" on the page.
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<StructureSection load='1g60' size='340' side='right'caption='[[1g60]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1g60]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Moraxella_bovis Moraxella bovis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G60 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G60 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
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{{STRUCTURE_1g60| PDB=1g60 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g60 OCA], [https://pdbe.org/1g60 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g60 RCSB], [https://www.ebi.ac.uk/pdbsum/1g60 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g60 ProSAT], [https://www.topsan.org/Proteins/MCSG/1g60 TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MTM2_MORBO MTM2_MORBO] This methylase recognizes the double-stranded sequence GAAGA, causes specific methylation on A-5, and protects the DNA from cleavage by the MboII endonuclease. It is not known if the cytosine of the complementary sequence TCTTC is also methylated by this enzyme.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g6/1g60_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g60 ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of Methyltransferase MboIIa (Moraxella bovis)===
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==See Also==
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*[[DNA methyltransferase 3D structures|DNA methyltransferase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12954781}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12954781 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12954781}}
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==About this Structure==
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1G60 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Moraxella_bovis Moraxella bovis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G60 OCA].
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==Reference==
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Crystal structure of MboIIA methyltransferase., Osipiuk J, Walsh MA, Joachimiak A, Nucleic Acids Res. 2003 Sep 15;31(18):5440-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12954781 12954781]
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[[Category: Moraxella bovis]]
[[Category: Moraxella bovis]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak A]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Osipiuk J]]
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[[Category: Osipiuk, J.]]
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[[Category: Walsh MA]]
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[[Category: Walsh, M A.]]
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[[Category: Dna methylation]]
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[[Category: Mcsg]]
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[[Category: Midwest center for structural genomic]]
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[[Category: Moraxella bovi]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: S-adenosylmethionine]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 14:15:26 2008''
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Current revision

Crystal Structure of Methyltransferase MboIIa (Moraxella bovis)

PDB ID 1g60

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