1jr7

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{{Seed}}
 
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[[Image:1jr7.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF GAB REVEALS OXIDOREDUCTASE FOLD==
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The line below this paragraph, containing "STRUCTURE_1jr7", creates the "Structure Box" on the page.
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<StructureSection load='1jr7' size='340' side='right'caption='[[1jr7]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1jr7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1jfy 1jfy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JR7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JR7 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>
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{{STRUCTURE_1jr7| PDB=1jr7 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jr7 OCA], [https://pdbe.org/1jr7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jr7 RCSB], [https://www.ebi.ac.uk/pdbsum/1jr7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jr7 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1jr7 TOPSAN]</span></td></tr>
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</table>
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===CRYSTAL STRUCTURE OF GAB REVEALS OXIDOREDUCTASE FOLD===
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== Function ==
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[https://www.uniprot.org/uniprot/GLAH_ECOLI GLAH_ECOLI] Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG) in the stationary phase of E.coli. Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. Other dicarboxylic acids (oxalate, malonate, succinate, adipate, and pimelate) are not substrates for this enzyme.<ref>PMID:30498244</ref>
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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1JR7 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1jfy 1jfy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JR7 OCA].
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Check<jmol>
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<jmolCheckbox>
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==Reference==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jr/1jr7_consurf.spt"</scriptWhenChecked>
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Structural genomics: a pipeline for providing structures for the biologist., Chance MR, Bresnick AR, Burley SK, Jiang JS, Lima CD, Sali A, Almo SC, Bonanno JB, Buglino JA, Boulton S, Chen H, Eswar N, He G, Huang R, Ilyin V, McMahan L, Pieper U, Ray S, Vidal M, Wang LK, Protein Sci. 2002 Apr;11(4):723-38. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11910018 11910018]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jr7 ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Burley, S K.]]
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[[Category: Large Structures]]
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[[Category: Lima, C D.]]
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[[Category: Burley SK]]
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[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
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[[Category: Lima CD]]
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[[Category: 2-oxoglutarate]]
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[[Category: Antibiotics biosynthesis]]
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[[Category: B-lactam]]
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[[Category: Ferrous oxygenase]]
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[[Category: Gaba]]
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[[Category: Gamma amino-butyric acid metabolism]]
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[[Category: New york structural genomix research consortium]]
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[[Category: Nysgxrc]]
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[[Category: Oxidoreductase]]
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[[Category: Oxygenase]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 15:05:29 2008''
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Current revision

CRYSTAL STRUCTURE OF GAB REVEALS OXIDOREDUCTASE FOLD

PDB ID 1jr7

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