2eo0
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:2eo0.png|left|200px]] | ||
| - | < | + | ==Crystal Structure of Holliday Junction Resolvase ST1444== |
| - | + | <StructureSection load='2eo0' size='340' side='right'caption='[[2eo0]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2eo0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurisphaera_tokodaii_str._7 Sulfurisphaera tokodaii str. 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EO0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EO0 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eo0 OCA], [https://pdbe.org/2eo0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eo0 RCSB], [https://www.ebi.ac.uk/pdbsum/2eo0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eo0 ProSAT], [https://www.topsan.org/Proteins/RSGI/2eo0 TOPSAN]</span></td></tr> | |
| - | + | </table> | |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HJC_SULTO HJC_SULTO] A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products. Inhibits the helicase activity of Hel308 (Hjm).[HAMAP-Rule:MF_01490]<ref>PMID:18296528</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eo/2eo0_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2eo0 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Resolvase 3D structures|Resolvase 3D structures]] | |
| - | + | == References == | |
| - | == | + | <references/> |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Kagawa | + | [[Category: Large Structures]] |
| - | [[Category: Kurumizaka | + | [[Category: Sulfurisphaera tokodaii str. 7]] |
| - | + | [[Category: Kagawa W]] | |
| - | [[Category: Sarai | + | [[Category: Kurumizaka H]] |
| - | [[Category: Yokoyama | + | [[Category: Sarai N]] |
| - | + | [[Category: Yokoyama S]] | |
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Current revision
Crystal Structure of Holliday Junction Resolvase ST1444
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