1sg7

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{{Seed}}
 
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[[Image:1sg7.png|left|200px]]
 
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==NMR solution structure of the putative cation transport regulator ChaB==
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The line below this paragraph, containing "STRUCTURE_1sg7", creates the "Structure Box" on the page.
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<StructureSection load='1sg7' size='340' side='right'caption='[[1sg7]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1sg7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SG7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SG7 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sg7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sg7 OCA], [https://pdbe.org/1sg7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sg7 RCSB], [https://www.ebi.ac.uk/pdbsum/1sg7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sg7 ProSAT], [https://www.topsan.org/Proteins/BSGI/1sg7 TOPSAN]</span></td></tr>
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{{STRUCTURE_1sg7| PDB=1sg7 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CHAB_ECO57 CHAB_ECO57] Might be a regulator of the sodium-potassium/proton antiporter ChaA.<ref>PMID:15306028</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sg/1sg7_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sg7 ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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BACKGROUND: ChaB is a putative regulator of ChaA, a Na+/H+ antiporter that also has Ca+/H+ activity in E. coli. ChaB contains a conserved 60-residue region of unknown function found in other bacteria, archaeabacteria and a series of baculoviral proteins. As part of a structural genomics project, the structure of ChaB was elucidated by NMR spectroscopy. RESULTS: The structure of ChaB is composed of 3 alpha-helices and a small sheet that pack tightly to form a fold that is found in the cyclin-box family of proteins. CONCLUSION: ChaB is distinguished from its putative DNA binding sequence homologues by a highly charged flexible loop region that has weak affinity to Mg2+ and Ca2+ divalent metal ions.
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===NMR solution structure of the putative cation transport regulator ChaB===
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The solution structure of ChaB, a putative membrane ion antiporter regulator from Escherichia coli.,Osborne MJ, Siddiqui N, Iannuzzi P, Gehring K BMC Struct Biol. 2004 Aug 11;4:9. PMID:15306028<ref>PMID:15306028</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_15306028}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 1sg7" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 15306028 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_15306028}}
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__TOC__
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</StructureSection>
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==About this Structure==
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1SG7 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SG7 OCA].
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==Reference==
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The solution structure of ChaB, a putative membrane ion antiporter regulator from Escherichia coli., Osborne MJ, Siddiqui N, Iannuzzi P, Gehring K, BMC Struct Biol. 2004 Aug 11;4:9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15306028 15306028]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: BSGI, Montreal-Kingston Bacterial Structural Genomics Initiative.]]
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[[Category: Large Structures]]
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[[Category: Cygler, M.]]
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[[Category: Cygler M]]
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[[Category: Gehring, K.]]
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[[Category: Gehring K]]
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[[Category: Osborne, M J.]]
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[[Category: Osborne MJ]]
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[[Category: Siddiqui, N.]]
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[[Category: Siddiqui N]]
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[[Category: Bsgi]]
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[[Category: Montreal-kingston bacterial structural genomics initiative]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 16:11:17 2008''
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Current revision

NMR solution structure of the putative cation transport regulator ChaB

PDB ID 1sg7

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