1xkl

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{{Seed}}
 
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[[Image:1xkl.png|left|200px]]
 
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==Crystal Structure of Salicylic Acid-binding Protein 2 (SABP2) from Nicotiana tabacum, NESG Target AR2241==
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The line below this paragraph, containing "STRUCTURE_1xkl", creates the "Structure Box" on the page.
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<StructureSection load='1xkl' size='340' side='right'caption='[[1xkl]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1xkl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Nicotiana_tabacum Nicotiana tabacum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XKL FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=STH:2-AMINO-4H-1,3-BENZOXATHIIN-4-OL'>STH</scene></td></tr>
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{{STRUCTURE_1xkl| PDB=1xkl | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xkl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xkl OCA], [https://pdbe.org/1xkl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xkl RCSB], [https://www.ebi.ac.uk/pdbsum/1xkl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xkl ProSAT], [https://www.topsan.org/Proteins/NESGC/1xkl TOPSAN]</span></td></tr>
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</table>
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===Crystal Structure of Salicylic Acid-binding Protein 2 (SABP2) from Nicotiana tabacum, NESG Target AR2241===
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== Function ==
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[https://www.uniprot.org/uniprot/SABP2_TOBAC SABP2_TOBAC] Required to convert methyl salicylate (MeSA) to salicylic acid (SA) as part of the signal transduction pathways that activate systemic acquired resistance in systemic tissue. MeSA is believed to be an inactive form that needs to be demethylated to exert a biological effect. Also able to catalyze the conversion of acibenzolar-S-methyl into acibenzolar to induce systemic acquired resistance.<ref>PMID:14673096</ref> <ref>PMID:15668381</ref> <ref>PMID:17916738</ref> <ref>PMID:19131332</ref> <ref>PMID:20621100</ref> <ref>PMID:20797615</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_15668381}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 15668381 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xk/1xkl_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_15668381}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1XKL is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Nicotiana_tabacum Nicotiana tabacum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKL OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xkl ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Structural and biochemical studies identify tobacco SABP2 as a methyl salicylate esterase and implicate it in plant innate immunity., Forouhar F, Yang Y, Kumar D, Chen Y, Fridman E, Park SW, Chiang Y, Acton TB, Montelione GT, Pichersky E, Klessig DF, Tong L, Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1773-8. Epub 2005 Jan 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15668381 15668381]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Nicotiana tabacum]]
[[Category: Nicotiana tabacum]]
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[[Category: Acton, T B.]]
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[[Category: Acton TB]]
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[[Category: Chen, Y.]]
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[[Category: Chen Y]]
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[[Category: Chiang, Y.]]
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[[Category: Chiang Y]]
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[[Category: Forouhar, F.]]
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[[Category: Forouhar F]]
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[[Category: Hunt, J F.]]
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[[Category: Hunt JF]]
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[[Category: Montelione, G T.]]
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[[Category: Montelione GT]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Tong L]]
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[[Category: Tong, L.]]
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[[Category: Alpha-beta protein]]
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[[Category: Nesg]]
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[[Category: Northeast structural genomics consortium]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 16:33:45 2008''
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Current revision

Crystal Structure of Salicylic Acid-binding Protein 2 (SABP2) from Nicotiana tabacum, NESG Target AR2241

PDB ID 1xkl

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